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一项关于青少年抑郁症患者一生中及某一时期内自残行为终身和现患率的荟萃分析。

A meta-analysis on the lifetime and period prevalence of self-injury among adolescents with depression.

机构信息

Emergency Department, The Affiliated Brain Hospital of Nanjing Medical University, Nanjing, Jiangsu, China.

Nursing Department, The Affiliated Brain Hospital of Nanjing Medical University, Nanjing, Jiangsu, China.

出版信息

Front Public Health. 2024 Jul 31;12:1434958. doi: 10.3389/fpubh.2024.1434958. eCollection 2024.

DOI:10.3389/fpubh.2024.1434958
PMID:39145175
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11322151/
Abstract

BACKGROUND

Adolescents are vulnerable to mental disorders due to physiological, psychosocial, and cognitive changes during this critical developmental stage. Depression, in particular, can lead to high-risk behaviors such as self-injury (SI) and suicide. This study aims to estimate the pooled prevalence of SI behaviors among adolescents with depression.

MATERIALS AND METHODS

We systematically searched databases including EMBASE, Scopus, PubMed, and Web of Sciences for relevant articles published on adolescents with depression from January 1, 2000, to January 1, 2024. The quality assessment of the studies was conducted using the Joanna Briggs Institute (JBI) criteria. The global prevalence of SI was calculated based on a random effects model using Stata software version 17.

RESULTS

Our analysis included 29 studies involving 12,934 adolescents. The lifetime prevalence of SI was 52% (95% Confidence Interval [CI]: 41-64), while the period prevalence was 57% (95% CI: 49-64). Notably, a significant relationship was observed between the prevalence of SI and the year of publication of articles ( = 0.002). Furthermore, publication bias was not significant for both lifetime prevalence ( = 0.281) and period prevalence (0.358).

CONCLUSION

The prevalence of self-injurious behaviors in adolescents with depression is alarmingly high, with more than half of adolescents having engaged in these high-risk behaviors during their lifetime or within the last year. Given the associated risk of suicide, it is crucial to identify individuals at risk and provide timely interventions.

摘要

背景

青少年在这个关键的发育阶段,由于生理、心理社会和认知的变化,容易出现精神障碍。特别是抑郁症会导致自伤(SI)和自杀等高危行为。本研究旨在估计患有抑郁症的青少年中 SI 行为的总患病率。

材料和方法

我们系统地检索了 EMBASE、Scopus、PubMed 和 Web of Sciences 数据库,以获取 2000 年 1 月 1 日至 2024 年 1 月 1 日期间发表的关于患有抑郁症的青少年的相关文章。使用 Joanna Briggs 研究所(JBI)标准对研究进行质量评估。使用 Stata 软件版本 17 基于随机效应模型计算 SI 的全球患病率。

结果

我们的分析包括 29 项研究,涉及 12934 名青少年。终生 SI 的患病率为 52%(95%置信区间 [CI]:41-64),而期间患病率为 57%(95% CI:49-64)。值得注意的是,SI 患病率与文章发表年份之间存在显著关系(=0.002)。此外,终生患病率(=0.281)和期间患病率(0.358)均无显著发表偏倚。

结论

患有抑郁症的青少年中自我伤害行为的患病率高得惊人,超过一半的青少年在其一生中或过去一年中曾有过这些高危行为。鉴于自杀的相关风险,识别风险个体并及时干预至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5485/11322151/144c205f002c/fpubh-12-1434958-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5485/11322151/ad3bd1454971/fpubh-12-1434958-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5485/11322151/0306277906fd/fpubh-12-1434958-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5485/11322151/64d2a2e48678/fpubh-12-1434958-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5485/11322151/144c205f002c/fpubh-12-1434958-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5485/11322151/ad3bd1454971/fpubh-12-1434958-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5485/11322151/0306277906fd/fpubh-12-1434958-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5485/11322151/64d2a2e48678/fpubh-12-1434958-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5485/11322151/144c205f002c/fpubh-12-1434958-g004.jpg

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