Malik Renuka, Goel Himanshi
Department of Obstetrics and Gynaecology, Atal Bihari Vajpayee Institute of Medical Sciences and PGIMER Dr Ram Manohar Lohia Hospital, New Delhi, India.
J Midlife Health. 2024 Apr-Jun;15(2):99-103. doi: 10.4103/jmh.jmh_226_23. Epub 2024 Jul 5.
To validate calf circumference as a reliable clinical tool for measuring muscle mass in postmenopausal women.
A cross sectional study done at Ram Manohar Lohia Hospital, New Delhi from February 2023 to September 2023. Thirty postmenopausal women were enrolled for this study. Women with surgical menopause, premature ovarian failure, chronic debilitating illness and morbid obesity were excluded. In these women, muscle mass was measured using calf circumference. Also, Appendicular skeletal muscle index (ASMI), a measure of muscle mass was calculated using DEXA scan (Gold standard). The muscle mass was taken as a parameter by both methods to detect sarcopenia. The collected data was analysed and statistically evaluated to clinically validate calf circumference as a reliable tool for measuring muscle mass in Indian postmenopausal women.
In our study, the values at different cut offs of calf circumference was compared to ASMI scoring using gold standard investigation DEXA Scan. The better accuracy was found for the cut off point 32 cm of calf circumference with sensitivity of 100%, specificity of 60%, positive predictive value of 71.4%, negative predictive value of 100% and accuracy of 80%. The prevalence of sarcopenia was found to be 70%.
Calf circumference can be used as reliable clinical tool to assess sarcopenia as a measure of muscle mass in Indian postmenopausal women.
验证小腿围作为测量绝经后女性肌肉量的可靠临床工具。
于2023年2月至2023年9月在新德里的拉姆·马诺哈尔·洛希亚医院进行了一项横断面研究。30名绝经后女性参与了本研究。排除接受手术绝经、卵巢早衰、慢性衰弱性疾病和病态肥胖的女性。在这些女性中，使用小腿围测量肌肉量。此外，使用双能X线吸收法扫描（金标准）计算肌肉量的指标——四肢骨骼肌指数（ASMI）。通过两种方法将肌肉量作为参数来检测肌肉减少症。对收集的数据进行分析和统计学评估，以临床验证小腿围作为测量印度绝经后女性肌肉量的可靠工具。
在我们的研究中，将不同小腿围切点处的值与使用金标准检查双能X线吸收法扫描的ASMI评分进行比较。发现小腿围切点为32 cm时准确性更高，敏感性为100%，特异性为60%，阳性预测值为71.4%，阴性预测值为100%，准确性为80%。发现肌肉减少症的患病率为70%。
小腿围可作为评估印度绝经后女性肌肉减少症（作为肌肉量的一种测量方法）的可靠临床工具。
