Rolland Yves, Lauwers-Cances Valérie, Cournot Maxime, Nourhashémi Fati, Reynish William, Rivière Daniel, Vellas Bruno, Grandjean Hélène
Internal Medicine Service and Gerontology Clinic, Hôpital La Grave-Casselardit, Toulouse, France.
J Am Geriatr Soc. 2003 Aug;51(8):1120-4. doi: 10.1046/j.1532-5415.2003.51362.x.
To determine whether calf circumference (CC), related to appendicular skeletal muscle mass, can be used as a measure of sarcopenia and is related to physical function.
Retrospective analysis of data from 1992 to 1994 of the European Patient Information and Documentation Systems Study.
Community setting in France.
One thousand four hundred fifty-eight French women aged 70 and older without previous history of hip fracture were recruited from the electoral lists.
Muscular mass was assessed using dual-energy x-ray absorptiometry (DEXA). CC was measured using a tape measure. Anthropometric measurements (height; weight; and waist, hip, and calf circumference), strength markers (grip strength), and self-reported physical function were also determined. Sarcopenia was defined (using DEXA) as appendicular skeletal muscle mass (weight (kg)/height (m2)) less than two standard deviations below the mean of a young female reference group.
The prevalence of sarcopenia was 9.5%. CC was correlated with appendicular skeletal muscle mass (r = 0.63). CC under 31 cm was the best clinical indicator of sarcopenia (sensitivity = 44.3%, specificity = 91.4%). CC under 31 cm was associated with disability and self-reported physical function but not sarcopenia (defined using DEXA), independent of age, comorbidity, obesity, income, health behavior, and visual impairment.
CC cannot be used to predict sarcopenia defined using DEXA but provides valuable information on muscle-related disability and physical function.
确定与附属骨骼肌质量相关的小腿围（CC）是否可作为肌肉减少症的一项指标，以及是否与身体功能相关。
对欧洲患者信息与文档系统研究1992年至1994年的数据进行回顾性分析。
法国的社区环境。
从选民名单中招募了1458名70岁及以上且无髋部骨折既往史的法国女性。
使用双能X线吸收法（DEXA）评估肌肉质量。使用卷尺测量小腿围。还测定了人体测量指标（身高、体重、腰围、臀围和小腿围）、力量指标（握力）以及自我报告的身体功能。肌肉减少症定义为（使用DEXA）附属骨骼肌质量（体重（kg）/身高（m²））低于年轻女性参考组均值两个标准差以下。
肌肉减少症的患病率为9.5%。小腿围与附属骨骼肌质量相关（r = 0.63）。小腿围小于31 cm是肌肉减少症的最佳临床指标（敏感性 = 44.3%，特异性 = 91.4%）。小腿围小于31 cm与残疾和自我报告的身体功能相关，但与（使用DEXA定义的）肌肉减少症无关，且独立于年龄、合并症、肥胖、收入、健康行为和视力损害。
小腿围不能用于预测使用DEXA定义的肌肉减少症，但可提供有关肌肉相关残疾和身体功能的有价值信息。
