School of Population Health, Faculty of Medicine and Health, UNSW Sydney, Sydney, Australia.
Centre of Public Health Sciences, Faculty of Medicine, University of Iceland, Reykjavík, Iceland.
Pharmacoepidemiol Drug Saf. 2024 Aug;33(8):e5887. doi: 10.1002/pds.5887.
The Medicines Intelligence (MedIntel) Data Platform is an anonymised linked data resource designed to generate real-world evidence on prescribed medicine use, effectiveness, safety, costs and cost-effectiveness in Australia.
The platform comprises Medicare-eligible people who are ≥18 years and residing in New South Wales (NSW), Australia, any time during 2005-2020, with linked administrative data on dispensed prescription medicines (Pharmaceutical Benefits Scheme), health service use (Medicare Benefits Schedule), emergency department visits (NSW Emergency Department Data Collection), hospitalisations (NSW Admitted Patient Data Collection) plus death (National Death Index) and cancer registrations (NSW Cancer Registry). Data are currently available to 2022, with approval to update the cohort and data collections annually. The platform includes 7.4 million unique people across all years, covering 36.9% of the Australian adult population; the overall population increased from 4.8 M in 2005 to 6.0 M in 2020. As of 1 January 2019 (the last pre-pandemic year), the cohort had a mean age of 48.7 years (51.1% female), with most people (4.4 M, 74.7%) residing in a major city. In 2019, 4.4 M people (73.3%) were dispensed a medicine, 1.2 M (20.5%) were hospitalised, 5.3 M (89.4%) had a GP or specialist appointment, and 54 003 people died. Anti-infectives were the most prevalent medicines dispensed to the cohort in 2019 (43.1%), followed by nervous system (32.2%) and cardiovascular system medicines (30.2%).
The MedIntel Data Platform creates opportunities for national and international research collaborations and enables us to address contemporary clinically- and policy-relevant research questions about quality use of medicines and health outcomes in Australia and globally.
药品智能(MedIntel)数据平台是一个匿名链接数据资源,旨在生成澳大利亚规定药物使用、疗效、安全性、成本和成本效益的真实世界证据。
该平台包括在 2005 年至 2020 年期间任何时间年满 18 岁并居住在新南威尔士州(NSW)的符合医疗保险资格的人,并链接了有关配药处方药物(药品福利计划)、医疗服务使用(医疗保险福利计划)、急诊就诊(新南威尔士州急诊部数据采集)、住院(新南威尔士州住院病人数据采集)、死亡(国家死亡指数)和癌症登记(新南威尔士州癌症登记处)的行政数据。目前数据可追溯至 2022 年,每年批准更新队列和数据采集。该平台涵盖了所有年份的 740 万独特人群,占澳大利亚成年人口的 36.9%;总人口从 2005 年的 480 万增加到 2020 年的 600 万。截至 2019 年 1 月 1 日(上一个大流行年前),队列的平均年龄为 48.7 岁(51.1%为女性),大多数人(440 万,74.7%)居住在主要城市。2019 年,440 万人(73.3%)配药,120 万人(20.5%)住院,530 万人(89.4%)看全科医生或专科医生,54003 人死亡。抗感染药是 2019 年配发给该队列的最常见药物(43.1%),其次是神经系统药物(32.2%)和心血管系统药物(30.2%)。
MedIntel 数据平台为国家和国际研究合作创造了机会,并使我们能够解决有关澳大利亚和全球药品合理使用和健康结果的当代临床和政策相关研究问题。