CBFA2T3-GLIS2 model of pediatric acute megakaryoblastic leukemia identifies FOLR1 as a CAR T cell target.
作者信息
Le Quy, Hadland Brandon, Smith Jenny L, Leonti Amanda, Huang Benjamin J, Ries Rhonda, Hylkema Tiffany A, Castro Sommer, Tang Thao T, McKay Cyd N, Perkins LaKeisha, Pardo Laura, Sarthy Jay, Beckman Amy K, Williams Robin, Idemmili Rhonda, Furlan Scott, Ishida Takashi, Call Lindsey, Srivastava Shivani, Loeb Anisha M, Milano Filippo, Imren Suzan, Morris Shelli M, Pakiam Fiona, Olson Jim M, Loken Michael R, Brodersen Lisa, Riddell Stanley R, Tarlock Katherine, Bernstein Irwin D, Loeb Keith R, Meshinchi Soheil
出版信息
J Clin Invest. 2024 Aug 15;134(16):e184305. doi: 10.1172/JCI184305.
Abstract
摘要
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CBFA2T3-GLIS2 model of pediatric acute megakaryoblastic leukemia identifies FOLR1 as a CAR T cell target.小儿急性巨核细胞白血病的CBFA2T3-GLIS2模型将FOLR1鉴定为嵌合抗原受体T细胞靶点。
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