Islamic International Medical College, Rawalpindi, Pakistan.
Neurosurg Rev. 2024 Aug 15;47(1):436. doi: 10.1007/s10143-024-02684-7.
This study reviews recent progress in the surgical treatment of Rathke's cleft cysts (RCCs) and Sellar region meningiomas, based on findings from three key studies. RCCs are benign, fluid-filled remnants from pituitary gland development that are usually asymptomatic and found by chance. However, surgical intervention is needed when they become symptomatic or increase in size. Research by Stefan Linsler et al. and others examines various surgical methods, including transcranial keyhole and transsphenoidal techniques for RCCs, and endoscopic endonasal and supraorbital keyhole approaches for Sellar meningiomas. The results show that both transcranial keyhole and transsphenoidal surgeries for RCCs have high success rates with no recurrences over 5.7 years, although the keyhole approach has fewer complications. For Sellar meningiomas, the choice between endoscopic endonasal and supraorbital keyhole techniques should be based on tumor characteristics, highlighting the importance of surgeon proficiency in both methods. These studies emphasize the need for personalized treatment strategies tailored to patient and tumor characteristics and highlight the importance of ongoing surgical skill development and further research to refine minimally invasive techniques. This study highlights the crucial role of personalized surgical approaches in improving outcomes for patients with RCCs and Sellar region meningiomas.
本研究基于三项关键研究，回顾了 Rathke 裂囊肿（RCC）和鞍区脑膜瘤的手术治疗的最新进展。RCC 是良性的、充满液体的垂体腺发育残留物，通常无症状，是偶然发现的。但当它们出现症状或增大时，就需要手术干预。Stefan Linsler 等人的研究探讨了各种手术方法，包括 RCC 的经颅锁孔和经蝶窦技术，以及鞍区脑膜瘤的内镜经鼻和眶上锁孔入路。结果表明，RCC 的经颅锁孔和经蝶窦手术成功率均很高，5.7 年以上无复发，但锁孔入路并发症较少。对于鞍区脑膜瘤，内镜经鼻和眶上锁孔技术的选择应根据肿瘤特征而定，这凸显了术者对这两种方法均熟练掌握的重要性。这些研究强调了根据患者和肿瘤特征制定个性化治疗策略的必要性，并突出了不断发展手术技能和进一步研究以完善微创技术的重要性。本研究强调了个性化手术方法在改善 RCC 和鞍区脑膜瘤患者治疗效果方面的关键作用。
