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一个用于恰加斯病研究的标准化临床数据库:NHEPACHA 网络。

A standardized clinical database for research in Chagas disease: The NHEPACHA network.

机构信息

Departamento de Investigación, Salvando Latidos A.C., Guadalajara, Mexico.

Departamento de Investigación, Instituto Cardiovascular de Mínima Invasión (ICMI), Guadalajara, Mexico.

出版信息

PLoS Negl Trop Dis. 2024 Aug 15;18(8):e0012364. doi: 10.1371/journal.pntd.0012364. eCollection 2024 Aug.

DOI:10.1371/journal.pntd.0012364
PMID:39146231
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11326575/
Abstract

The NHEPACHA Iberoamerican Network, founded on the initiative of a group of researchers from Latin American countries and Spain, aims to establish a research framework for Chagas disease that encompasses diagnosis and treatment. For this purpose, the network has created a questionnaire to gather relevant data on epidemiological, clinical, diagnostic, and therapeutic aspects of the disease. This questionnaire was developed based on a consensus of expert members of the network, with the intention of collecting high-quality standardized data, which can be used interchangeably by the different research centers that make up the NHEPACHA network. Furthermore, the network intends to offer a clinical protocol that can be embraced by other researchers, facilitating comparability among published studies, as well as the development of therapeutic response and progression markers.

摘要

NHEPACHA 伊比利亚美洲网络由来自拉丁美洲国家和西班牙的一组研究人员发起成立,旨在建立一个涵盖奇卡氏病诊断和治疗的研究框架。为此,该网络创建了一份问卷,以收集有关该病流行病学、临床、诊断和治疗方面的相关数据。该问卷是根据网络的专家成员的共识制定的,目的是收集高质量的标准化数据,供 NHEPACHA 网络中的不同研究中心互换使用。此外,该网络还打算提供一个可以被其他研究人员采用的临床方案,以促进已发表研究之间的可比性,并开发治疗反应和进展标志物。

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PLoS Negl Trop Dis. 2024 Aug 15;18(8):e0012364. doi: 10.1371/journal.pntd.0012364. eCollection 2024 Aug.
2
Chagas disease.恰加斯病
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本文引用的文献

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Chagas Disease in Europe.欧洲的恰加斯病
Trop Med Infect Dis. 2023 Dec 1;8(12):513. doi: 10.3390/tropicalmed8120513.
2
Biomarkers for the diagnosis, treatment follow-up, and prediction of cardiac complications in Chagas disease in chronic phase: Recent advances.用于诊断、治疗随访和预测慢性期恰加斯病心脏并发症的生物标志物:最新进展。
Parasite Immunol. 2023 Dec;45(12):e13013. doi: 10.1111/pim.13013. Epub 2023 Oct 5.
3
Avoiding Clinical Trial Failures in Neglected Tropical Diseases: The Example of Chagas Disease.避免被忽视热带病临床试验失败:以恰加斯病为例。
Clin Infect Dis. 2023 Apr 17;76(8):1516-1520. doi: 10.1093/cid/ciac884.
4
Two-dimensional strain derived parameters provide independent predictors of progression to Chagas cardiomyopathy and mortality in patients with Chagas disease.二维应变衍生参数可为恰加斯病患者发展为恰加斯心肌病及死亡提供独立的预测指标。
Int J Cardiol Heart Vasc. 2022 Jan 10;38:100955. doi: 10.1016/j.ijcha.2022.100955. eCollection 2022 Feb.
5
Chagas Disease across Contexts: Scientific Knowledge in a Globalized World.不同背景下的恰加斯病:全球化世界中的科学知识
Med Anthropol. 2021 Aug-Sep;40(6):572-589. doi: 10.1080/01459740.2021.1946805. Epub 2021 Jul 8.
6
New regimens of benznidazole monotherapy and in combination with fosravuconazole for treatment of Chagas disease (BENDITA): a phase 2, double-blind, randomised trial.苯达唑单药及联合福沙韦仑治疗恰加斯病的新方案(BENDITA):一项 2 期、双盲、随机试验。
Lancet Infect Dis. 2021 Aug;21(8):1129-1140. doi: 10.1016/S1473-3099(20)30844-6. Epub 2021 Apr 6.
7
Benznidazole decreases the risk of chronic Chagas disease progression and cardiovascular events: A long-term follow up study.苯硝唑可降低慢性恰加斯病进展和心血管事件的风险:一项长期随访研究。
EClinicalMedicine. 2020 Dec 23;31:100694. doi: 10.1016/j.eclinm.2020.100694. eCollection 2021 Jan.
8
Risk of Chronic Cardiomyopathy Among Patients With the Acute Phase or Indeterminate Form of Chagas Disease: A Systematic Review and Meta-analysis.慢性克山病患者在急性期或不定型期的风险:系统评价和荟萃分析。
JAMA Netw Open. 2020 Aug 3;3(8):e2015072. doi: 10.1001/jamanetworkopen.2020.15072.
9
[Synthesis of evidence: Guidance for the diagnosis and treatment of Chagas diseaseSíntese de evidências: Guia de diagnóstico e tratamento da doença de Chagas].[证据综合:恰加斯病诊断与治疗指南。恰加斯病诊断与治疗指南的证据综合]
Rev Panam Salud Publica. 2020 Jun 8;44:e28. doi: 10.26633/RPSP.2020.28. eCollection 2020.
10
State-of-the-art in host-derived biomarkers of Chagas disease prognosis and early evaluation of anti-Trypanosoma cruzi treatment response.关于恰加斯病预后的宿主来源生物标志物的最新研究进展和抗克氏锥虫治疗反应的早期评估。
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