Li Hai-Bo, He Xiao-Qing, Pang Qian-Qian, Wang Zhen-Zhong, Zhang Yong-Wen, Yao Xin-Sheng, Yu Yang
Institute of Traditional Chinese Medicine & Natural Products, College of Pharmacy; State Key Laboratory of Bioactive Molecules and Druggability Assessment; International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development of Ministry of Education (MOE) of China; Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, Jinan University, Guangzhou, China.
State Key Laboratory on Technologies for Chinese Medicine Pharmaceutical Process Control and Intelligent Manufacture, Jiangsu Kanion Pharmaceutical Co. Ltd, Jiangsu, Lianyungang, China.
Nat Prod Res. 2024 Aug 15:1-8. doi: 10.1080/14786419.2024.2386396.
Four previously unreported phenylpropanoid glycosides (-), together with four known analogues (-), were isolated from the leaves of . The structures of these new compounds were elucidated based on spectroscopic analysis (HR-ESI-MS, NMR, IR, UV) and chemical methods. In addition, the neuroprotective activities of all the isolates were evaluated by measuring their cell viability in HO-induced OLN-93 cell injury model.
从……的叶子中分离出四种先前未报道的苯丙素苷(-)以及四种已知类似物(-)。基于光谱分析(高分辨电喷雾电离质谱、核磁共振、红外光谱、紫外光谱)和化学方法阐明了这些新化合物的结构。此外,通过在过氧化氢诱导的OLN - 93细胞损伤模型中测量细胞活力,评估了所有分离物的神经保护活性。