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从[植物名称]叶子中分离得到的四种新苯丙素苷及其神经保护活性。 (注:原文中“and their neuroprotective activities”前的“of”后缺少具体植物名称,这里翻译时补充了“[植物名称]”,以使句子完整通顺。)

Four new phenylpropanoid glycosides from the leaves of and their neuroprotective activities.

作者信息

Li Hai-Bo, He Xiao-Qing, Pang Qian-Qian, Wang Zhen-Zhong, Zhang Yong-Wen, Yao Xin-Sheng, Yu Yang

机构信息

Institute of Traditional Chinese Medicine & Natural Products, College of Pharmacy; State Key Laboratory of Bioactive Molecules and Druggability Assessment; International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development of Ministry of Education (MOE) of China; Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, Jinan University, Guangzhou, China.

State Key Laboratory on Technologies for Chinese Medicine Pharmaceutical Process Control and Intelligent Manufacture, Jiangsu Kanion Pharmaceutical Co. Ltd, Jiangsu, Lianyungang, China.

出版信息

Nat Prod Res. 2024 Aug 15:1-8. doi: 10.1080/14786419.2024.2386396.

Abstract

Four previously unreported phenylpropanoid glycosides (-), together with four known analogues (-), were isolated from the leaves of . The structures of these new compounds were elucidated based on spectroscopic analysis (HR-ESI-MS, NMR, IR, UV) and chemical methods. In addition, the neuroprotective activities of all the isolates were evaluated by measuring their cell viability in HO-induced OLN-93 cell injury model.

摘要

从……的叶子中分离出四种先前未报道的苯丙素苷(-)以及四种已知类似物(-)。基于光谱分析(高分辨电喷雾电离质谱、核磁共振、红外光谱、紫外光谱)和化学方法阐明了这些新化合物的结构。此外,通过在过氧化氢诱导的OLN - 93细胞损伤模型中测量细胞活力,评估了所有分离物的神经保护活性。

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