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用于常规计算机断层扫描检查的成年和儿科患者的大小特异性有效剂量的系数的确定。

The determination of coefficients for size specific effective dose for adult and pediatric patients undergoing routine computed tomography examinations.

机构信息

Department of Radiological Technology, Faculty of Allied Health Sciences, Naresuan University, Phitsanulok, Thailand.

Department of Clinical Physics and Bio-engineering, University of Glasgow, Glasgow G12 8QQ, United Kingdom.

出版信息

J Radiol Prot. 2024 Aug 28;44(3). doi: 10.1088/1361-6498/ad6faa.

DOI:10.1088/1361-6498/ad6faa
PMID:39146953
Abstract

The effective dose resulting from computed tomography (CT) scans provides an assessment of the risk associated with stochastic effects but does not account for the patient's size. Advances in Monte Carlo simulations offer the potential to obtain organ dose data from phantoms of varying stature, enabling derivation of a size-specific effective doses (SEDs) representing doses to individual patients. This study aimed to compute size-specific k-conversion factors for SED in routine CT examinations for adult and pediatric patients of different sizes. Radiation interactions were simulated for adult and pediatric phantom models of various sizes using National Cancer Institute CT version 3.0.20211123. Subsequent calculations of SED were performed, and coefficients for SED were derived, considering the variations in body sizes. The results revealed a strong correlation between effective diameter and weight, observed with size-specific k-conversion factors for adult and pediatric phantoms, respectively. While size-specific k-conversion factors for CT brain remained constant in adults, values for pediatric cases varied. When using the tube current modulation (TCM) system, size-specific k-conversion factors increased in larger phantoms and decreased in smaller ones. The extent of this increase or decrease correlated with the set TCM strength. This study provides coefficients for estimating SEDs in routine CT exams. Software utilizing look-up tables of coefficients can be used to provide dose information for CT scanners at local hospitals, offering guidance to practitioners on doses to individual patients and improving radiation risk awareness in clinical practice.

摘要

计算机断层扫描(CT)扫描的有效剂量可评估与随机效应相关的风险,但无法考虑患者的体型。蒙特卡罗模拟的进步为从不同体型的体模中获取器官剂量数据提供了可能性,从而可以得出代表个体患者剂量的特定体型有效剂量(SED)。本研究旨在计算不同体型的成年和儿科患者常规 CT 检查的特定体型 k 转换系数以计算 SED。使用美国国立癌症研究所 CT 版本 3.0.20211123 对各种体型的成年和儿科体模模型进行了辐射相互作用模拟。随后进行了 SED 的计算,并考虑了体型的变化,得出了 SED 的系数。结果表明,有效直径与体重之间存在很强的相关性,分别观察到成年和儿科体模的特定体型 k 转换系数。虽然成人 CT 脑的特定体型 k 转换系数保持不变,但儿科病例的值有所不同。使用管电流调制(TCM)系统时,较大的体模中的特定体型 k 转换系数增加,而较小的体模中的特定体型 k 转换系数减小。这种增加或减少的程度与设定的 TCM 强度相关。本研究提供了估算常规 CT 检查中 SED 的系数。可以使用利用系数查找表的软件为当地医院的 CT 扫描仪提供剂量信息,为从业者提供针对个体患者的剂量信息,并提高临床实践中的辐射风险意识。

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