Department of Cardiac Surgery, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, California.
Division of Cardiovascular Surgery, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania.
Ann Thorac Surg. 2024 Dec;118(6):1236-1244. doi: 10.1016/j.athoracsur.2024.07.031. Epub 2024 Aug 13.
Contemporary national outcomes of open and endovascular aortic repair for descending thoracic aortic aneurysms (DTAAs) and thoracoabdominal aortic aneurysms (TAAAs) are unclear. This study evaluated this issue by using The Society of Thoracic Surgeons (STS) Adult Cardiac Surgery Database (ACSD).
From July 1, 2017 to June 30, 2022, study investigators identified 3522 adults who underwent planned DTAA repair (open, 328; endovascular, 1895) or TAAA repair (open, 870; endovascular, 429), after excluding ascending aorta or aortic arch aneurysms (zone 0, 1, or 2), interventions with a proximal extent in zone 0 or zone 1, juxtarenal or infrarenal aortic interventions, hybrid procedures, aortic trauma, and aortic infection.
Most DTAA interventions (85.2%) were endovascular repairs, whereas most TAAA interventions were open repairs (66.9%). For DTAA interventions, the operative mortality, permanent stroke rate, and rate of spinal cord injury were 4.2%, 3.8%, and 2.4% for endovascular repairs and 9.2%, 8.5%, and 4.6% for open repairs, respectively (all P < .05). For TAAA interventions, the operative mortality, permanent stroke rate, and rate of spinal cord injury were 6.5%, 2.1%, and 3.0% for endovascular repairs and 11.7%, 6.0%, and 12.2% for open repairs, respectively (all P < .05). Increasing annual open TAAA repair volume was associated with lower odds of experiencing the composite of operative mortality, permanent stroke, or spinal cord injury.
On the basis of STS ACSD data, endovascular repair was the predominant approach for treating DTAA, whereas most patients undergoing TAAA interventions had an open surgical repair. Outcome differences between open and endovascular approaches may be related to patient selection. Increasing center experience with open TAAA repair is associated with improved outcomes.
目前尚不清楚开放和血管内主动脉修复术治疗降主动脉夹层动脉瘤(DTAA)和胸腹主动脉瘤(TAAA)的当代国家结局。本研究使用胸外科医师学会(STS)成人心脏外科学数据库(ACSD)对此进行了评估。
2017 年 7 月 1 日至 2022 年 6 月 30 日,研究人员排除升主动脉或主动脉弓动脉瘤(0 区、1 区或 2 区)、近端位于 0 区或 1 区的介入治疗、肾下或肾周主动脉介入治疗、杂交手术、主动脉外伤和主动脉感染后,确定了 3522 名计划行 DTAA 修复(开放手术 328 例,血管内 1895 例)或 TAAA 修复(开放手术 870 例,血管内 429 例)的成年人。
大多数 DTAA 干预措施(85.2%)为血管内修复,而大多数 TAAA 干预措施为开放修复(66.9%)。对于 DTAA 干预,血管内修复的手术死亡率、永久性中风发生率和脊髓损伤发生率分别为 4.2%、3.8%和 2.4%,而开放修复分别为 9.2%、8.5%和 4.6%(均 P<0.05)。对于 TAAA 干预,血管内修复的手术死亡率、永久性中风发生率和脊髓损伤发生率分别为 6.5%、2.1%和 3.0%,而开放修复分别为 11.7%、6.0%和 12.2%(均 P<0.05)。开放 TAAA 修复年手术量的增加与手术死亡率、永久性中风或脊髓损伤的复合发生率降低有关。
根据 STS ACSD 数据,血管内修复是治疗 DTAA 的主要方法,而大多数接受 TAAA 干预的患者接受了开放手术修复。开放和血管内方法之间的结果差异可能与患者选择有关。开放 TAAA 修复中心经验的增加与结果的改善有关。