Kamiguchi H, Ohkubo T, Yamamura M, Katsunuma T
Tokai J Exp Clin Med. 1985 Jun;10(2-3):165-8.
The levels of alpha 1-antichymotrypsin (ACT) was monitored in patients who underwent bone marrow transplantation. Seven received HLA-identical sibling bone marrow grafts, two received transplants from twins and one was given HLA-nonidentical marrow from his father. A dramatic increase of ACT was observed in all patients who developed graft-versus-host disease (GvHD). ACT did not rise at all in the case of patients who received marrow from twins, even in a patient who was given three transplants from the same donor. The patient transplanted from his father died from GvHD and the increase of ACT was the greatest fluctuation measured.
对接受骨髓移植的患者监测了α1-抗糜蛋白酶（ACT）水平。7名患者接受了人类白细胞抗原（HLA）匹配的同胞骨髓移植，2名接受了双胞胎的移植，1名接受了来自其父亲的HLA不匹配骨髓。在所有发生移植物抗宿主病（GvHD）的患者中均观察到ACT显著升高。接受双胞胎骨髓移植的患者中ACT根本没有升高，即使是一名接受了来自同一供体的三次移植的患者也是如此。从其父亲处接受移植的患者死于GvHD，ACT的升高是所测量到的最大波动。
