Hajj Jihane, Schneider Andrea L C, Jacoby Douglas, Schreiber James, Nolfi David, Turk Melanie T
J Cardiovasc Nurs. 2025;40(3):228-249. doi: 10.1097/JCN.0000000000001125. Epub 2024 Aug 16.
A limited understanding exists on the associations of neighborhood environment with subclinical atherosclerosis and its progression.
The purpose of this integrative review was to explore associations of neighborhood environments and socioeconomic status (SES) with subclinical atherosclerosis and its long-term progression.
Three themes were identified: environmental exposure affects the natural history of atherosclerosis, neighborhood characteristics are associated with subclinical atherosclerosis, and individual SES is associated with development and progression of subclinical atherosclerosis more so than neighborhood SES. Some variations in results were noted based on the vascular site examined.
Disadvantaged neighborhoods and low SES are associated with greater subclinical atherosclerosis. Inconsistencies in a few studies seemed to be related to lack of coronary artery progression among the relatively young adults. This suggests further examination is needed of the contextual associations of neighborhood and SES with markers of generalized atherosclerosis, such as carotid intima-media thickness.
对于邻里环境与亚临床动脉粥样硬化及其进展之间的关联，人们的了解有限。
本整合性综述的目的是探讨邻里环境和社会经济地位（SES）与亚临床动脉粥样硬化及其长期进展之间的关联。
确定了三个主题：环境暴露影响动脉粥样硬化的自然病程，邻里特征与亚临床动脉粥样硬化相关，个体SES比邻里SES更与亚临床动脉粥样硬化的发生和进展相关。根据所检查的血管部位，结果存在一些差异。
处境不利的社区和低SES与更严重的亚临床动脉粥样硬化相关。少数研究中的不一致似乎与相对年轻成年人中冠状动脉进展的缺乏有关。这表明需要进一步研究邻里和SES与全身性动脉粥样硬化标志物（如颈动脉内膜中层厚度）之间的背景关联。
