Lassus A
Curr Med Res Opin. 1979;6(3):165-7. doi: 10.1185/03007997909109415.
Forty patients with symmetrical eczematous lesions on their extremities were treated in a double-blind fashion with 0.05% clobetasone butyrate and 0.1% hydrocortisone butyrate in cream bases. After 2 weeks of treatment, a preference for clobetasone butyrate was observed in 7 cases, for hydrocortisone butyrate in 9 cases and in 24 cases both sides responded equally. The lesions on both sides improved steadily throughout the study in all cases. When completing the trial after 2-weeks' treatment, the clobetasone butyrate-treated lesions had healed in 8 cases and the hydrocortisone butyrate-treated lesions in 10 cases. No local side-effects were observed.
40例四肢对称性湿疹样皮损患者采用双盲法，分别使用含0.05%丁酸氯倍他松和0.1%丁酸氢化可的松的乳膏基质进行治疗。治疗2周后，7例患者更倾向于使用丁酸氯倍他松，9例更倾向于使用丁酸氢化可的松，24例两侧反应相同。在整个研究过程中，所有病例两侧的皮损均稳步改善。治疗2周结束试验时，丁酸氯倍他松治疗的皮损有8例愈合，丁酸氢化可的松治疗的皮损有10例愈合。未观察到局部副作用。
