• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

The evolving role of GLP-1 agonists in ischemic stroke prevention in diabetic patients.

作者信息

Shankar Aditi, Sharma Aditi, Buch Chirag, Chilton Robert J

机构信息

Division of Cardiology, Department of Medicine, University of Texas Health San Antonio, San Antonio, Texas, USA.

出版信息

Cardiovasc Endocrinol Metab. 2024 Aug 14;13(3):e00308. doi: 10.1097/XCE.0000000000000308. eCollection 2024 Sep.

DOI:10.1097/XCE.0000000000000308
PMID:39148946
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11326472/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3af2/11326472/ba97172c0699/xce-13-e00308-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3af2/11326472/f5d093927869/xce-13-e00308-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3af2/11326472/ba97172c0699/xce-13-e00308-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3af2/11326472/f5d093927869/xce-13-e00308-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3af2/11326472/ba97172c0699/xce-13-e00308-g002.jpg

相似文献

1
The evolving role of GLP-1 agonists in ischemic stroke prevention in diabetic patients.胰高血糖素样肽-1激动剂在糖尿病患者缺血性卒中预防中不断演变的作用。
Cardiovasc Endocrinol Metab. 2024 Aug 14;13(3):e00308. doi: 10.1097/XCE.0000000000000308. eCollection 2024 Sep.
2
GLP-1RAs for Ischemic Stroke Prevention in Patients With Type 2 Diabetes Without Established Atherosclerotic Cardiovascular Disease.在无已确诊动脉粥样硬化性心血管疾病的2型糖尿病患者中，使用胰高血糖素样肽-1受体激动剂预防缺血性卒中
Diabetes Care. 2022 May 1;45(5):1184-1192. doi: 10.2337/dc21-1993.
3
GLP-1 receptor agonists in diabetes for stroke prevention: a systematic review and meta-analysis.GLP-1 受体激动剂在糖尿病中的应用与卒中预防：一项系统评价和荟萃分析。
J Neurol. 2020 Jul;267(7):2117-2122. doi: 10.1007/s00415-020-09813-4. Epub 2020 Apr 4.
4
GLP-1 Receptor Agonists and Risk of Adverse Cerebrovascular Outcomes in Type 2 Diabetes: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.GLP-1 受体激动剂与 2 型糖尿病患者不良脑血管结局风险：一项随机对照试验的系统评价和荟萃分析。
J Clin Endocrinol Metab. 2023 Jun 16;108(7):1806-1812. doi: 10.1210/clinem/dgad076.
5
Protection against stroke with glucagon-like peptide-1 receptor agonists: a comprehensive review of potential mechanisms.用胰高血糖素样肽-1 受体激动剂预防中风：潜在机制的综合综述。
Cardiovasc Diabetol. 2022 Nov 15;21(1):242. doi: 10.1186/s12933-022-01686-3.
6
Risks of stroke, its subtypes and atrial fibrillation associated with glucagon-like peptide 1 receptor agonists versus sodium-glucose cotransporter 2 inhibitors: a real-world population-based cohort study in Hong Kong.胰高血糖素样肽-1受体激动剂与钠-葡萄糖协同转运蛋白2抑制剂相关的中风风险、其亚型及心房颤动：一项基于香港真实世界人群的队列研究
Cardiovasc Diabetol. 2023 Feb 24;22(1):40. doi: 10.1186/s12933-023-01772-0.
7
Relationship between Glucagon-like Peptide-1 Receptor Agonists and Cardiovascular Disease in Chronic Respiratory Disease and Diabetes.胰高血糖素样肽-1受体激动剂与慢性呼吸系统疾病和糖尿病患者心血管疾病之间的关系
Biomedicines. 2024 Feb 22;12(3):488. doi: 10.3390/biomedicines12030488.
8
Reducing Ischemic Stroke in Diabetes: The Role of GLP-1 RAs.降低糖尿病患者的缺血性脑卒中风险：GLP-1RA 的作用。
J Fam Pract. 2023 Jul;72(6 Suppl):S55-S60. doi: 10.12788/jfp.0624.
9
Glucagonlike peptide-1 receptor agonists versus dipeptidyl peptidase-4 inhibitors in ischemic strokes with diabetes 2.胰高血糖素样肽-1 受体激动剂与二肽基肽酶-4 抑制剂在伴有 2 型糖尿病的缺血性卒中中的比较
Eur J Neurol. 2024 Aug;31(8):e16329. doi: 10.1111/ene.16329. Epub 2024 May 7.
10
Neuroprotective Mechanisms of Glucagon-Like Peptide-1-Based Therapies in Ischemic Stroke: An Update Based on Preclinical Research.基于胰高血糖素样肽-1的疗法在缺血性卒中中的神经保护机制：基于临床前研究的最新进展
Front Neurol. 2022 Mar 15;13:844697. doi: 10.3389/fneur.2022.844697. eCollection 2022.

本文引用的文献

1
Risk of stroke and retinopathy during GLP-1 receptor agonist cardiovascular outcome trials: An eight RCTs meta-analysis.GLP-1 受体激动剂心血管结局试验期间的卒中与视网膜病变风险：八项 RCTs 的荟萃分析。
Front Endocrinol (Lausanne). 2022 Dec 5;13:1007980. doi: 10.3389/fendo.2022.1007980. eCollection 2022.
2
2021 Guideline for the Prevention of Stroke in Patients With Stroke and Transient Ischemic Attack: A Guideline From the American Heart Association/American Stroke Association.《2021年卒中与短暂性脑缺血发作患者卒中预防指南：美国心脏协会/美国卒中协会指南》
Stroke. 2021 Jul;52(7):e364-e467. doi: 10.1161/STR.0000000000000375. Epub 2021 May 24.
3
GLP-1 receptor agonists in diabetes for stroke prevention: a systematic review and meta-analysis.
GLP-1 受体激动剂在糖尿病中的应用与卒中预防：一项系统评价和荟萃分析。
J Neurol. 2020 Jul;267(7):2117-2122. doi: 10.1007/s00415-020-09813-4. Epub 2020 Apr 4.
4
The glucagon-like peptide-1 receptor agonist reduces inflammation and blood-brain barrier breakdown in an astrocyte-dependent manner in experimental stroke.胰高血糖素样肽-1 受体激动剂以星形胶质细胞依赖的方式减轻实验性中风中的炎症和血脑屏障破坏。
J Neuroinflammation. 2019 Nov 28;16(1):242. doi: 10.1186/s12974-019-1638-6.
5
Protection against stroke with glucagon-like peptide 1 receptor agonists: a systematic review and meta-analysis.用胰高血糖素样肽 1 受体激动剂预防中风：系统评价和荟萃分析。
Eur J Neurol. 2019 Apr;26(4):559-565. doi: 10.1111/ene.13905. Epub 2019 Jan 30.
6
Neural mechanisms in remote ischaemic conditioning in the heart and brain: mechanistic and translational aspects.心脏和大脑中的远程缺血预处理的神经机制：机制和转化方面。
Basic Res Cardiol. 2018 Jun 1;113(4):25. doi: 10.1007/s00395-018-0684-z.
7
Prevention of cardiovascular events in Asian patients with ischaemic stroke at high risk of cerebral haemorrhage (PICASSO): a multicentre, randomised controlled trial.亚洲缺血性脑卒中高危脑出血风险患者的心血管事件预防（PICASSO）：一项多中心、随机对照试验。
Lancet Neurol. 2018 Jun;17(6):509-518. doi: 10.1016/S1474-4422(18)30128-5.
8
Presynaptic GLP-1 receptors enhance the depolarization-evoked release of glutamate and GABA in the mouse cortex and hippocampus.突触前 GLP-1 受体增强了谷氨酸和 GABA 在小鼠大脑皮层和海马中的去极化诱发释放。
Biofactors. 2018 Mar;44(2):148-157. doi: 10.1002/biof.1406. Epub 2017 Dec 19.
9
Anti-inflammatory Effect of Glucagon Like Peptide-1 Receptor Agonist, Exendin-4, through Modulation of IB1/JIP1 Expression and JNK Signaling in Stroke.胰高血糖素样肽-1受体激动剂艾塞那肽-4通过调节IκB1/JIP1表达和JNK信号传导对中风的抗炎作用
Exp Neurobiol. 2017 Aug;26(4):227-239. doi: 10.5607/en.2017.26.4.227. Epub 2017 Aug 31.
10
Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes.司美格鲁肽与 2 型糖尿病患者的心血管结局
N Engl J Med. 2016 Nov 10;375(19):1834-1844. doi: 10.1056/NEJMoa1607141. Epub 2016 Sep 15.