Dargent D, Rudigoz R C, Audra P, Adelline P
Biomed Pharmacother. 1985;39(8):414-21.
The authors report a series of 434 patients with invasive cancer of the uterine cervix treated with primary surgery. The results are equivalent to those reported by others who treated cervix cancer with radiotherapy. Post-operative radiotherapy did not improve the results except in the most advanced forms (pT2b, pN1 or 2) when it increases the disease-free interval without altering the survival probability at 5 years. For the clinical stages I, IIA and IIB proximal (infiltration of the parametrium limited to the proximal part) surgery is the elective treatment. In stage IIB distal and for "operable" Stages III and IV, a combination of chemotherapy-surgery and radiotherapy is suggested.
作者报告了434例接受原发手术治疗的子宫颈浸润癌患者。结果与其他采用放射治疗子宫颈癌的报告相当。术后放疗除在最晚期（pT2b、pN1或2）可增加无病间期而不改变5年生存概率外，并未改善结果。对于临床分期I、IIA和IIB近端（宫旁浸润局限于近端部分），手术是首选治疗方法。对于IIB远端期以及“可手术的”III期和IV期，建议采用化疗-手术和放疗相结合的方法。
