Dunn Raymond L, Costello Caitriona, Borchardt Jackson M, Sprague Daniel Y, Chiu Grace C, Miller Julia M, L'Etoile Noelle, Kato Saul
Weill Institute of Neurosciences, University of California San Francisco.
Department of Cell and Tissue Biology, University of California San Francisco.
bioRxiv. 2024 Aug 11:2024.08.11.607402. doi: 10.1101/2024.08.11.607402.
We report the existence of a working memory system in the nematode that is employed for deferred action in a sensory-guided decision-making process. We find that the turn direction of discrete reorientations during navigation is under sensory-guided control and relies on a working memory that can persist over an intervening behavioral sequence. This memory system is implemented by the phasic interaction of two distributed oscillatory dynamical components. The interaction of oscillatory neural ensembles may be a conserved primitive of cognition across the animal kingdom.
我们报告了线虫中存在一种工作记忆系统，该系统用于在感官引导的决策过程中进行延迟行动。我们发现，线虫在导航过程中离散重新定向的转向方向受感官引导控制，并依赖于一种可在中间行为序列中持续存在的工作记忆。这个记忆系统由两个分布式振荡动力学组件的相位相互作用实现。振荡神经集群的相互作用可能是整个动物界认知的一种保守原基。
