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互联网+可穿戴设备训练对脑卒中患者肢体功能恢复及血清神经细胞因子含量的影响。

Internet + wearable device training effects on limb function recovery and serum neurocytokine content in stroke patients.

机构信息

Department of Rehabilitation Medicine, The Affiliated Rehabilitation Hospital of Chongqing Medical University, Chongqing, China.

Department of Cardiopulmonary Rehabilitation, The Affiliated Rehabilitation Hospital of Chongqing Medical University, Chongqing, China.

出版信息

NeuroRehabilitation. 2024;55(1):17-28. doi: 10.3233/NRE-230347.

DOI:10.3233/NRE-230347
PMID:39150836
Abstract

BACKGROUND

The traditional method of post-hospital intervention and guidance of stroke patients has some limitations.

OBJECTIVE

To investigate the effects of Internet + wearable device training on limb function recovery and the levels of serum neurocytokines (BDNF, NT-3, and NGF) in stroke patients.

METHODS

80 stroke patients with hemiplegia were randomly selected from the Department of Neurorehabilitation, Affiliated Rehabilitation Hospital of Chongqing Medical University. They were divided into a control group and an observation group, with 40 patients in each group. The control group received routine post-hospital follow-up guidance, while the observation group received Internet remote home rehabilitation guidance combined with wearable device training. The interventions were compared between the two groups.

RESULTS

At 4 weeks and 12 weeks after discharge, the observation group showed higher scores on the Fugl-Meyer scale (FMA), Berg Balance Scale (BBS), modified Barthel Index (MBI), stride length, gait speed, gait frequency, and higher levels of BDNF, NT-3, and NGF. Additionally, the observation group had lower scores on the Hamilton Anxiety and Depression Scale (HADS) (P < 0.05).

CONCLUSIONS

The application of Internet remote home rehabilitation guidance combined with wearable device training in stroke patients with hemiplegia can improve limb function recovery. It effectively increases the levels of BDNF, NT-3, and NGF, promoting the nutritional repair of damaged nerves. These findings hold clinical significance.

摘要

背景

传统的脑卒中患者出院后干预和指导方法存在一定局限性。

目的

探讨互联网+可穿戴设备训练对脑卒中患者肢体功能恢复及血清神经细胞因子(BDNF、NT-3、NGF)水平的影响。

方法

选取重庆医科大学附属康复医院神经康复科收治的 80 例脑卒中偏瘫患者,采用随机数字表法分为对照组和观察组,每组 40 例。对照组患者接受常规出院后随访指导,观察组患者接受互联网远程居家康复指导+可穿戴设备训练。比较两组患者的干预效果。

结果

出院后 4 周、12 周,观察组患者的 Fugl-Meyer 量表(FMA)、Berg 平衡量表(BBS)、改良巴氏指数(MBI)评分、步长、步速、步频均高于对照组,BDNF、NT-3、NGF 水平高于对照组,汉密尔顿焦虑量表(HAMA)、汉密尔顿抑郁量表(HAMD)评分低于对照组(P<0.05)。

结论

互联网远程居家康复指导+可穿戴设备训练应用于脑卒中偏瘫患者,可促进患者肢体功能恢复,提高 BDNF、NT-3、NGF 水平,促进受损神经的营养修复,具有一定的临床意义。

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