Department of Gerontology and Geriatrics, Shengjing Hospital of China Medical University, Shenyang, Liaoning 110004, China; Department of Health Statistics, School of Public Health, China Medical University, Shenyang, Liaoning 110122, China; Beijing Institute for Brain Disorders, Capital Medical University, Beijing 100069, China.
School of Medicine, University of Electronic Science and Technology of China, Chengdu, Sichuan 610054, China.
J Affect Disord. 2024 Nov 15;365:87-94. doi: 10.1016/j.jad.2024.08.080. Epub 2024 Aug 14.
To explore the relationship between adverse childhood experiences and falls in older adults, and the mediating effects of depression on such associations.
This is a prospective study used survey data from the China Health and Retirement Longitudinal Study. Twelve expanded ACEs obtained from the 2014 Life History Survey. Depression levels were assessed using the Centre for Epidemiologic Studies Depression Scale-10. Self-reported outcomes of falling evaluated based on "Have you fallen down since the last survey?" and "How many times have you fallen down seriously enough to need medical treatment?" Logistic regression models were used to explore the relationship between ACEs with falls and recurrent falls. Poisson regression models were used to explore the relationship between ACEs and number of severe falls. Besides, mediation analysis was used to explore whether depression mediates the relationship between ACEs and falls in older adults.
The more adverse childhood experiences experienced, the higher the risk of fall and recurrent falls, and the more severe the falls. Additionally, depression partially mediated the relationship between adverse childhood experiences and falls. Besides, middle-aged individuals were more susceptible to the impact of adverse childhood experiences on falls than older individuals, especially males.
Exposure to adverse childhood experiences is associated with falls in older adults, and depression partially mediates this association. Middle-aged adults were more susceptible to the impact of adverse childhood experiences on falls. These offer important information for clinical practice and public health interventions to prevent falls and reduce fall-related injuries among older adults.
探讨老年人不良童年经历与跌倒之间的关系，以及抑郁对这种关联的中介作用。
这是一项使用中国健康与退休纵向研究调查数据进行的前瞻性研究。从 2014 年生活史调查中获得了 12 个扩展 ACEs。抑郁水平使用流行病学研究抑郁量表-10 进行评估。根据“自上次调查以来你是否跌倒过？”和“你有多少次严重跌倒需要治疗？”来评估自我报告的跌倒结果。使用逻辑回归模型探讨 ACEs 与跌倒和复发性跌倒之间的关系。使用泊松回归模型探讨 ACEs 与严重跌倒次数之间的关系。此外，还进行了中介分析，以探讨抑郁是否在老年人的 ACEs 和跌倒之间起中介作用。
经历的不良童年经历越多，跌倒和复发性跌倒的风险越高，跌倒越严重。此外，抑郁部分中介了不良童年经历与跌倒之间的关系。此外，中年个体比老年个体更容易受到不良童年经历对跌倒的影响，尤其是男性。
暴露于不良童年经历与老年人跌倒有关，抑郁部分中介了这种关联。中年个体比老年个体更容易受到不良童年经历对跌倒的影响。这些为临床实践和公共卫生干预措施提供了重要信息，以预防老年人跌倒和减少与跌倒相关的伤害。
