Suppr超能文献

高血压与心房颤动:高血压对心房颤动消融围手术期结局的临床影响及其最佳控制以预防复发。

Hypertension and atrial fibrillation: the clinical impact of hypertension on perioperative outcomes of atrial fibrillation ablation and its optimal control for the prevention of recurrence.

机构信息

Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University School of Medicine, Shimotsuke, Japan.

出版信息

Hypertens Res. 2024 Oct;47(10):2800-2810. doi: 10.1038/s41440-024-01796-3. Epub 2024 Aug 16.

Abstract

Hypertension (HTN) is one of the major risk factors for developing atrial fibrillation (AF), and it has been estimated that approximately 70% of hypertensive patients are at risk of developing AF. On the other hand, 60-80% of AF patients have HTN. These two diseases share many risk factors such as diabetes mellitus, obesity, alcohol consumption, and sleep apnea syndrome during their onset and disease progression. The mutual presence of these diseases has the potential to create a negative spiral, exacerbating each other's impact and ultimately leading to cardiovascular events such as heart failure and cerebrovascular disorders, thereby increasing mortality rates. With regard to the treatment of HTN, the variety of antihypertensive drugs and treatment options have significantly increased. Alongside the widespread adoption of antihypertensive therapy, a certain level of efficacy has been recognized in suppressing the incidence of new-onset AF. Catheter ablation is an established and effective treatment for AF. However, a notable recurrence rate persists. In recent years, management of these multiple risk factors has been recognized to be essential for suppressing AF recurrence, and recent guidelines for AF underscore the significance of proactively managing these risks before treatment. Notably, effective HTN management assumes paramount importance given its impact on the morbidity of AF patients. This review summarizes the correlation between HTN control before and after ablation and the risk of AF recurrence. The focus is on elucidating the pathophysiological background and its impact on clinical outcomes.

摘要

高血压(HTN)是发生心房颤动(AF)的主要危险因素之一,据估计,约 70%的高血压患者有发生 AF 的风险。另一方面,60-80%的 AF 患者有 HTN。这两种疾病在发病和疾病进展过程中有许多共同的危险因素,如糖尿病、肥胖、饮酒和睡眠呼吸暂停综合征。这些疾病的共同存在有可能形成一个恶性循环,相互加重影响,最终导致心力衰竭和脑血管疾病等心血管事件,从而增加死亡率。关于 HTN 的治疗,降压药物的种类和治疗选择显著增加。随着降压治疗的广泛应用,在抑制新发 AF 的发生率方面已取得一定的疗效。导管消融是治疗 AF 的一种已确立且有效的方法。然而,仍存在显著的复发率。近年来,人们认识到管理这些多种危险因素对于抑制 AF 复发至关重要,最近的 AF 指南强调在治疗前积极管理这些风险的重要性。值得注意的是,有效控制 HTN 对于 AF 患者的发病率至关重要。这篇综述总结了消融前后 HTN 控制与 AF 复发风险之间的相关性。重点阐述了病理生理背景及其对临床结局的影响。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验