Department of Gastroenterology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710061, China.
Clinical Medical Research Center for Digestive Diseases (Oncology) of Shaanxi Province, Xi'an, 710061, China.
BMC Gastroenterol. 2024 Aug 17;24(1):268. doi: 10.1186/s12876-024-03320-w.
Research on Irritable Bowel Syndrome (IBS) among medical students has increased globally, highlighting a high prevalence in this demographic. However, there is a lack of data specifically regarding the prevalence of IBS among medical students in Yemen. This study aimed to investigate the prevalence and associated factors of IBS among Yemeni medical students.
We conducted a cross-sectional study involving medical students who completed a validated self-administered questionnaire incorporating socio-demographic information, dietary habits, smoking status, sleep patterns, and the Rome IV criteria for IBS. We used bivariate and multivariate logistic regression models to identify IBS's associated factors, estimated as odds ratios (ORs) with 95% confidence intervals (CIs) and average marginal effect (AME) on the predicted probability of IBS.
The study included 351 medical students with a mean age of 22.53 ± 2.70 years; 39.60% (139) were females. The prevalence of IBS was 26.21% (92 students), with 67.39% (62) of them classified as IBS-M (mixed). In multivariable analysis, the consumption of carbonated soft drinks remained significantly associated with IBS (OR: 3.35; 95% CI: 1.14-9.88; P = 0.028). In males, coffee consumption had a substantial effect on the predicted probability of IBS (AME: 11.41%; 95% CI: 0.32-22.60). In females, the consumption of carbonated soft drinks had a significant effect on the predicted probability of IBS (AME: 24.91%; 95% CI: 8.34-41.48).
The consumption of carbonated soft drinks is significantly associated with IBS among medical students, with a particularly notable increase in the predicted probability of IBS in females. These findings highlight the necessity for gender-specific dietary recommendations in IBS management. Further research is essential to investigate IBS in the general population to gain a comprehensive understanding of its prevalence and associated factors.
全球范围内对医学生肠易激综合征（IBS）的研究有所增加，这表明这一人群中 IBS 的患病率较高。然而，针对也门医学生中 IBS 的患病率，目前还缺乏具体的数据。本研究旨在调查也门医学生中 IBS 的患病率及相关因素。
我们进行了一项横断面研究，纳入了完成包含社会人口学信息、饮食习惯、吸烟状况、睡眠模式以及罗马 IV 标准的 IBS 自填式问卷的医学生。我们使用二变量和多变量逻辑回归模型来确定 IBS 的相关因素，结果以比值比（OR）和 95%置信区间（CI）以及对 IBS 预测概率的平均边际效应（AME）表示。
研究纳入了 351 名平均年龄为 22.53±2.70 岁的医学生，其中 39.60%（139 名）为女性。IBS 的患病率为 26.21%（92 名学生），其中 67.39%（62 名）为 IBS-M（混合）型。多变量分析显示，饮用碳酸软饮料与 IBS 显著相关（OR：3.35；95%CI：1.14-9.88；P=0.028）。对于男性，咖啡的摄入对 IBS 的预测概率有显著影响（AME：11.41%；95%CI：0.32-22.60）。对于女性，饮用碳酸软饮料对 IBS 的预测概率有显著影响（AME：24.91%；95%CI：8.34-41.48）。
饮用碳酸软饮料与医学生的 IBS 显著相关，女性中 IBS 的预测概率显著增加。这些发现强调了针对 IBS 管理，有必要制定针对不同性别的饮食建议。进一步的研究对于调查一般人群中的 IBS 患病率及其相关因素至关重要，以全面了解 IBS。
