Coulaud J P, Le Bras J, Matheron S, Morinière B, Saimot A G, Rossignol J F
Bull Soc Pathol Exot Filiales. 1985;78(5 Pt 2):965-70.
Halofantrine is a 9-phenanthrene-methanol effective against multiresistant strains of Plasmodium falciparum. It is extremely effective and well-tolerated in treating cases of malaria imported into France. 1,500 mg in 3 doses at 8 hour intervals produced 100% cure rate in semi-immune patients. This dosage could be repeated after 14 days in order to obtain the same cure rate in non-immune patients. Side-effects are minor and include epigastric pain, nausea and one case of skin rash.
卤泛群是一种9-菲甲醇，对多重耐药恶性疟原虫菌株有效。它在治疗输入法国的疟疾病例方面极其有效且耐受性良好。每8小时1次，分3次服用1500毫克，对半免疫患者的治愈率达100%。14天后可重复此剂量，以便在非免疫患者中获得相同的治愈率。副作用较小，包括上腹部疼痛、恶心和1例皮疹。
