Carr M E, Gabriel D A
J Emerg Med. 1985;3(6):449-52. doi: 10.1016/0736-4679(85)90003-4.
Medications and renal failure are common causes of qualitative platelet disorders. Epistaxis occurring in these settings may be unresponsive to conventional therapy. Two patients with epistaxis and platelet dysfunction are presented who were successfully treated with porcine nasal packing. The technique, previously shown effective in thrombocytopenic patients, is inexpensive, simple, and effective. The procedure is described and its possible modes of action are discussed. The pathogenesis of platelet disorders induced by uremia and aspirin are also briefly discussed.
药物和肾衰竭是血小板质量异常的常见原因。在这些情况下发生的鼻出血可能对传统治疗无反应。本文介绍了两名鼻出血和血小板功能障碍患者,他们通过猪鼻填塞成功治愈。该技术此前已被证明对血小板减少症患者有效,价格低廉、操作简单且效果显著。本文描述了该操作过程,并讨论了其可能的作用方式。还简要讨论了尿毒症和阿司匹林引起的血小板疾病的发病机制。