Department of Ophthalmology, National Health Insurance Service Ilsan Hospital, Goyang, Korea.
Department of Ophthalmology, Yonsei University College of Medicine, Seoul, Korea.
Korean J Ophthalmol. 2024 Oct;38(5):354-363. doi: 10.3341/kjo.2024.0008. Epub 2024 Aug 16.
This study aimed to analyze the incidence and characteristics of intraocular lens (IOL) dislocation after cataract surgery in South Korea.
We retrospectively analyzed the incidence of IOL dislocation after cataract surgery in patients diagnosed between 2002 and 2021. Data of all pseudophakic patients who underwent secondary IOL or IOL exchange surgeries due to IOL dislocation were extracted from the Korean National Health Insurance System database and the Korean Standard Classification of Diseases 7th Revision codes. The incidence per 1,000,000 person-years and corresponding 95% confidence intervals (CIs) were calculated.
Between 2002 and 2021, 39,965 of the 4,848,125 pseudophakic patients (0.82%) were diagnosed with IOL dislocation and surgically treated. The incidence of IOL dislocation requiring surgery in pseudophakic patients was 28,900 per 1,000,000 person-years (95% CI, 28,431-29,369), comprising 57,800 cases in male (95% CI, 56,730-58,870) and 10,800 in female patients (95% CI, 10,523-11,077), and the mean male to female ratio was 5.35. The incidence rate peaked in younger age group below 40 years, showing 107,000 per 1,000,000 person-years (95% CI, 102,900-111,100), and the average age of IOL dislocation requiring surgery was 68.1 ± 10.7 years. The average time lapse from cataract surgery to secondary IOL surgery due to IOL dislocation was 4.1 ± 4.7 years (median, 2.2 years), and the number of secondary IOL surgery due to dislocation of artificial lensrapidly occurred 10 years after cataract surgery among all age groups.
The incidence of IOL dislocation requiring surgery was higher in younger and male patients. Our findings could be expected to aid establishing future healthcare policies for South Korean populations with an increased risk of IOL dislocation after cataract surgery.
本研究旨在分析韩国白内障手术后人工晶状体(IOL)脱位的发生率和特征。
我们回顾性分析了 2002 年至 2021 年间白内障手术后 IOL 脱位的发生率。从韩国国家健康保险系统数据库和韩国疾病分类第 7 版代码中提取所有因 IOL 脱位而接受二次 IOL 或 IOL 置换手术的假性晶状体患者的数据。计算每 100 万人年的发生率及其相应的 95%置信区间(CI)。
2002 年至 2021 年间,在 4848125 名假性晶状体患者中,有 39965 名(0.82%)被诊断为 IOL 脱位并接受了手术治疗。假性晶状体患者中需要手术治疗的 IOL 脱位发生率为每 100 万人年 28900 例(95%CI,28431-29369),其中男性 57800 例(95%CI,56730-58870),女性 10800 例(95%CI,10523-11077),男女比例为 5.35。发病率在 40 岁以下的年轻人群中达到峰值,为每 100 万人年 107000 例(95%CI,102900-111100),需要手术治疗的 IOL 脱位的平均年龄为 68.1±10.7 岁。从白内障手术到因 IOL 脱位进行二次 IOL 手术的平均时间间隔为 4.1±4.7 年(中位数为 2.2 年),在所有年龄组中,白内障手术后 10 年,因人工晶状体脱位而进行的二次 IOL 手术数量迅速增加。
需要手术治疗的 IOL 脱位发生率在年轻和男性患者中较高。我们的研究结果有望为韩国白内障手术后人工晶状体脱位风险增加的人群制定未来的医疗保健政策提供帮助。