Kintzinger Kristina, Rothaus Kai, Faatz Henrik, Lommatzsch Claudia, Lommatzsch Albrecht, Gutfleisch Matthias, Lange Clemens, Koch Jörg M
Augenzentrum am St. Franziskus-Hospital Münster, Hohenzollernring 74, 48145, Münster, Deutschland.
Achim Wessing Institut für ophthalmopathologische Diagnostik, Universitätsklinikum Essen-Duisburg, Essen, Deutschland.
Ophthalmologie. 2025 May 6. doi: 10.1007/s00347-025-02240-8.
Late intraocular lens (IOL) dislocation is the second most common late complication after successful cataract surgery. It also represents the most common cause of IOL explantations. An increasing incidence of this complication has already been described in the literature since 1995. The aim of this study is to observe the development of the incidence of IOL dislocation within our department over the last 10 years and to identify and evaluate possible risk factors.
In this retrospective monocentric analysis, a total of 578 eyes of 544 patients, who had undergone surgery for an IOL dislocation within the last 10 years, were included. The presence of myopia, pseudoexfoliation, prior vitrectomy or intravitreal injection (IVI), traumatic events and use of topical prostaglandin therapy were analyzed as possible risk factors.
Since 2017, there has been an increase in the incidence of IOL dislocations (R = 0.45). On average, the dislocations occurred 11.7 years after cataract surgery, at an age of 75.6 ± 11 years. Myopia was present in 62% of the patients, of which 40.6% had high myopia. Pseudoexfoliation was documented in 38% of cases. No clear correlations were found for the further analyzed factors, such as prior prostaglandin therapy, IVI or trauma.
Due to the increasing number of cataract surgeries, a further increase in the incidence of IOL dislocations is to be expected in the future. The presence of possible risk factors for IOL dislocation and the age of the patient should therefore be taken into consideration prior to indication of cataract surgery and IOL selection.
人工晶状体（IOL）脱位是白内障手术成功后第二常见的晚期并发症。它也是人工晶状体取出术最常见的原因。自1995年以来，该并发症的发生率在文献中已有报道呈上升趋势。本研究的目的是观察过去10年我院人工晶状体脱位发生率的变化，并确定和评估可能的危险因素。
在这项回顾性单中心分析中，纳入了过去10年内接受过人工晶状体脱位手术的544例患者的578只眼。分析近视、假性剥脱、既往玻璃体切除术或玻璃体内注射（IVI）、外伤事件以及局部前列腺素治疗的使用情况作为可能的危险因素。
自2017年以来，人工晶状体脱位的发生率有所增加（R = 0.45）。平均而言，脱位发生在白内障手术后11.7年，患者年龄为75.6±11岁。62%的患者存在近视，其中40.6%为高度近视。38%的病例记录有假性剥脱。对于进一步分析的因素，如既往前列腺素治疗、玻璃体内注射或外伤，未发现明显相关性。
由于白内障手术数量的增加，预计未来人工晶状体脱位的发生率会进一步上升。因此，在进行白内障手术和选择人工晶状体之前，应考虑人工晶状体脱位可能的危险因素以及患者的年龄。
