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肥胖患者使用安比尤®奥瑞加因TM进行插管时斜坡卧位与嗅物位的比较:一项随机对照研究

Ramped versus sniffing position for Ambu® AuraGainTM insertion in patients with obesity: a randomized controlled study.

作者信息

Jeong Hye-Won, Bae Hong-Beom, Lee Leyeoin, Lee Woojeong, Kim Joungmin

机构信息

Department of Anesthesiology and Pain Medicine, Chonnam National University Hospital, Gwangju, Korea.

Department of Anesthesiology and Pain Medicine, Chonnam National University Hwasun Hospital, Hwasun, Korea.

出版信息

Korean J Anesthesiol. 2024 Oct;77(5):518-525. doi: 10.4097/kja.24255. Epub 2024 Aug 19.

Abstract

BACKGROUND

The ramped position facilitates mask ventilation and endotracheal intubation in patients with obesity. This study aimed to determine whether the ramped position improves supraglottic airway (SGA) insertion in patients with obesity.

METHODS

In this prospective, randomized, single-center trial, 48 obese patients undergoing elective surgery were randomized into either ramped or sniffing position groups. The Ambu® AuraGainTM (Ambu A/S), a second-generation SGA, was used. The primary outcome was the time required for the AuraGain insertion. Secondary outcomes included ease and number of insertion attempts, oropharyngeal leak pressure (OLP), and complications. The number needed to treat (NNT) was calculated to ensure ease of insertion.

RESULTS

The time required for the AuraGain insertion was significantly shorter in the ramped group than in the sniffing group (13.0 [11.0, 16.0] vs. 24.0 [21.0, 28.0], P < 0.001). The insertion was easier in the ramped group than in the sniffing group (23/24 vs. 13/24, NNT = 2.4 [95% CI, 1.6, 5.0], P = 0.003). The first-attempt success rate was higher in the ramped group than in the sniffing group, although the difference was not statistically significant (22/24 vs. 18/24, P = 0.319). The OLP and postoperative complication rates were not significantly different between the groups.

CONCLUSIONS

The ramped position reduced the time required for the AuraGain insertion in obese patients while providing comparable airway sealing without increasing adverse events. Therefore, a ramped position may be a more suitable option for SGA insertion in this population.

摘要

背景

斜坡卧位有助于肥胖患者的面罩通气和气管插管。本研究旨在确定斜坡卧位是否能改善肥胖患者声门上气道(SGA)置入情况。

方法

在这项前瞻性、随机、单中心试验中,48例接受择期手术的肥胖患者被随机分为斜坡卧位组或嗅物位组。使用第二代SGA——Ambu® AuraGainTM(丹麦Ambu公司)。主要结局指标为AuraGain置入所需时间。次要结局指标包括置入尝试的难易程度和次数、口咽漏气压(OLP)及并发症。计算治疗所需人数(NNT)以确保置入的 ease(此处“ease”可能有误,推测为“成功率”之类意思,暂按原词)。

结果

斜坡卧位组AuraGain置入所需时间显著短于嗅物位组(13.0 [11.0, 16.0] 对比 24.0 [21.0, 28.0],P < 0.001)。斜坡卧位组的置入操作比嗅物位组更容易(23/24对比13/24,NNT = 2.4 [95% CI,1.6, 5.0],P = 0.003)。斜坡卧位组首次尝试成功率高于嗅物位组,尽管差异无统计学意义(22/24对比18/24,P = 0.319)。两组间OLP及术后并发症发生率无显著差异。

结论

斜坡卧位缩短了肥胖患者AuraGain置入所需时间,同时提供了相当的气道密封效果且未增加不良事件。因此,斜坡卧位可能是该人群SGA置入更合适的选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b8d/11467505/26c06ca83202/kja-24255f1.jpg

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