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术后认知功能障碍:综述

Postoperative Cognitive Dysfunction: A Review.

作者信息

Anand Neelesh, Gupta Reetika, Mishra Shashi Prakash, Mishra Manjaree

机构信息

Department of Anesthesiology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, India.

Department of General Surgery, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, India.

出版信息

Asian J Anesthesiol. 2024 Dec 20;62(1):1-11. doi: 10.6859/aja.202403_62(1).0001. Epub 2024 Aug 1.

Abstract

Elderly patients are more vulnerable to cognitive dysfunction in the postoperative period. Patients who are apparently well in cognitive functions in the preoperative period after undergoing anesthesia in noncardiac surgery will develop symptoms of cognitive dysfunction. Postoperative cognitive dysfunction (POCD) doesn't continue for a long duration and usually undergoes self-resolution. Proper definitions and congruous tests for diagnosis are absent. Rigorous preoperative assessment of cognitive function and distinguishing risk factors are indispensable for recognizing the range of POCD and its association with surgery and anesthesia. Recent studies haven't revealed any anesthesia technique or drug which can significantly reduce the incidence of POCD. Therefore, giving accurate information to patients can be challenging.

摘要

老年患者在术后更容易出现认知功能障碍。在非心脏手术中接受麻醉后,术前认知功能看似正常的患者会出现认知功能障碍症状。术后认知功能障碍(POCD)持续时间不长,通常会自行缓解。目前缺乏关于POCD的恰当定义和一致的诊断测试。对认知功能进行严格的术前评估并识别风险因素,对于明确POCD的范围及其与手术和麻醉的关联至关重要。最近的研究尚未发现任何能显著降低POCD发生率的麻醉技术或药物。因此,向患者提供准确信息可能具有挑战性。

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