Department of Radiotherapy, Hannover Medical School, Hannover, Germany.
CCC Hannover (Claudia von Schilling Center), Klaus Bahlsen Center for Integrative Oncology, Hannover Medical School, Hannover, Germany.
Integr Cancer Ther. 2024 Jan-Dec;23:15347354241269931. doi: 10.1177/15347354241269931.
Cancer often causes reduced resilience, quality of life (QoL) and poorer overall well-being. To mitigate these problems, complementary and alternative medicine (CAM) is widely used among patients with cancer. This study aimed to evaluate the long-term effects of an interdisciplinary integrative oncology group-based program (IO-GP) on the resilience and use of CAM in patients with cancer.
This was a prospective, observational, single-center study. Resilience (RS-13), CAM usage (I-CAM-G), QoL (SF-12) and health-related lifestyle factor (nutrition, smoking, alcohol consumption and physical exercise) data were collected for 70 patients who participated in a 10-week IO-GP between January 2019 and June 2022 due to cancer. The IO-GP is offered at the setting of a university hospital and is open to adult patients with cancer. It contains elements from mind-body medicine and positive psychology, as well as recommendations on healthy diet, exercise and CAM approaches. Patients who completed the IO-GP at least 12 months prior (1-4.5 years ago) were included in this study. Statistical analysis included descriptive analysis and parametric and nonparametric tests to identify significant differences ( < .05).
Resilience increased significantly ≥12 months after participation in the IO-GP (n = 44, = .006, = 8.274) and had a medium effect size ( = .410). The time since the IO-GP was completed ("12-24 months," "24-36 months," and ">36 months") showed no statistically significant interaction with changes in resilience ( = .226, = 1.544). The most frequently used CAM modalities within the past 12 months were vitamins/minerals (85.7%), relaxation techniques (54.3%), herbs and plant medicine (41.1%), yoga (41.4%) and meditation (41.4%). The IO-GP was the most common source informing study participants about relaxation techniques (n = 24, 64.9%), meditation (n = 21, 72.4%) and taking vitamin D (n = 16, 40.0%). Significantly greater levels of resilience were found in those practicing meditation ( = .010, = -.642) or visualization ( = .003, = -.805) compared to non-practitioners.
IO-GPs have the potential to empower patients with cancer to continue using CAM practices-especially from mind-body medicine-even 1 to 4.5 years after completing the program. Additionally, resilience levels increased. These findings provide notable insight into the long-term effects of integrative oncology interventions on resilience and the use of CAM, especially in patients with breast cancer.
癌症常导致患者的适应力下降、生活质量（QoL）下降和整体健康状况恶化。为了缓解这些问题，癌症患者广泛使用补充和替代医学（CAM）。本研究旨在评估基于跨学科整合肿瘤学小组的方案（IO-GP）对癌症患者适应力和 CAM 使用的长期影响。
这是一项前瞻性、观察性、单中心研究。70 名癌症患者参与了 10 周的 IO-GP，研究收集了他们的适应力（RS-13）、CAM 使用（I-CAM-G）、生活质量（SF-12）和健康相关生活方式因素（营养、吸烟、饮酒和体育锻炼）的数据。IO-GP 在大学医院进行，面向癌症成年患者，包含身心医学和积极心理学元素，以及关于健康饮食、运动和 CAM 方法的建议。本研究纳入了至少在 12 个月前（1-4.5 年前）完成 IO-GP 的患者。统计分析包括描述性分析和参数和非参数检验，以确定显著差异（ < .05）。
参加 IO-GP 后 12 个月以上，适应力显著增加（n = 44， = .006， = 8.274），且具有中等效应量（ = .410）。IO-GP 完成时间（“12-24 个月”、“24-36 个月”和“>36 个月”）与适应力变化之间没有统计学上的显著交互作用（ = .226， = 1.544）。在过去 12 个月内，最常使用的 CAM 方式是维生素/矿物质（85.7%）、放松技术（54.3%）、草药和植物药（41.1%）、瑜伽（41.4%）和冥想（41.4%）。IO-GP 是最常见的信息来源，告知研究参与者放松技术（n = 24，64.9%）、冥想（n = 21，72.4%）和服用维生素 D（n = 16，40.0%）。与非练习者相比，练习冥想（ = .010， = -.642）或可视化（ = .003， = -.805）的患者具有更高的适应力水平。
IO-GP 有可能使癌症患者能够继续使用 CAM 实践，特别是在完成方案 1 至 4.5 年后——这是一种从身心医学获得的力量。此外，适应力水平有所提高。这些发现为综合肿瘤学干预对适应力和 CAM 使用的长期影响提供了重要的见解，特别是在乳腺癌患者中。
