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战争与癌症:在一项随机综合肿瘤学研究中探索患者的故事

War and Cancer: Exploring Patient Narratives in a Randomized Integrative Oncology Study.

作者信息

Ben-Arye Eran, Gressel Orit, Keshet Yael, Zaritsky Vika, Kassem Sameer, Segev Yakir, Samuels Noah

机构信息

Integrative Oncology Program, The Oncology Service; Lin, Carmel, and Zebulun Medical Centers, Clalit Health Services, Haifa, Israel.

Ruth and Bruch Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel.

出版信息

Psychooncology. 2025 May;34(5):e70172. doi: 10.1002/pon.70172.

DOI:10.1002/pon.70172
PMID:40326225
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12053034/
Abstract

STUDY OBJECTIVE

The current war in Israel has affected quality of life (QoL)-related concerns among patients with cancer. Integrative oncology (IO) provides complementary medicine within supportive and palliative care. The study examined an IO program in northern Israel for cancer and war-related concerns.

METHODS

This qualitative study, nested within a prospective randomized controlled trial, examined patients undergoing oncology and palliative care expressing cancer and war-related QoL concerns referred by oncology healthcare providers to an IO program. Patients were randomized to manual-relaxation with (Group A) or without (Group B) acupuncture. Narratives were recorded in MYCaW (Measure Yourself Concerns and Well-being) questionnaires immediately and after 24 h. Narrative excerpts were qualitatively analyzed using ATLAS.Ti software for systematic coding.

RESULTS

Patient narratives (Group A, 67; Group B, 58) focused primarily on themes which included a sense of calmness and reduced emotional distress (e.g., stress, anxiety, worries, nervousness), more prominently in Group B (manual-relaxation only; 55/56 immediately/after 24 h); and reduced pain severity, more so in Group A (with acupuncture; 19/24). Most excerpts described improved QoL in both groups (142/147, 97%) immediately after IO treatments, less so at 24 h (103/135).

CONCLUSIONS

Narratives of patients facing cancer- and war-related QoL challenges due to the ongoing war in Israel describe a beneficial impact of IO treatments, both immediately and after 24 h. Manual-relaxation without acupuncture was more likely to improve emotional concerns, with pain relief more apparent with the addition of acupuncture. Further qualitative and quantitative research is needed to explore these findings.

摘要

研究目的

以色列当前的战争影响了癌症患者与生活质量(QoL)相关的问题。综合肿瘤学(IO)在支持性和姑息性护理中提供补充医学。本研究调查了以色列北部一个针对癌症及与战争相关问题的IO项目。

方法

本定性研究嵌套于一项前瞻性随机对照试验中,研究对象为接受肿瘤学和姑息性护理的患者,这些患者表达了与癌症和战争相关的生活质量问题,由肿瘤医疗服务提供者转介至一个IO项目。患者被随机分为接受(A组)或不接受(B组)针灸的手法放松组。在MYCaW(自我评估问题与幸福感)问卷中,分别在即时和24小时后记录患者的叙述。使用ATLAS.Ti软件对叙述摘录进行定性分析,以进行系统编码。

结果

患者叙述(A组67例;B组58例)主要集中在以下主题上,包括平静感和情绪困扰减轻(如压力、焦虑、担忧、紧张),在B组(仅手法放松组)更为明显(即时/24小时后分别为55/56例);疼痛严重程度减轻,在A组(接受针灸组)更为显著(19/24例)。大多数摘录描述了两组在IO治疗后即时生活质量均有所改善(142/147,97%),在24小时时改善程度较小(103/135)。

结论

由于以色列持续的战争而面临与癌症和战争相关生活质量挑战的患者叙述表明,IO治疗在即时和24小时后均产生了有益影响。不进行针灸的手法放松更有可能改善情绪问题,而添加针灸后疼痛缓解更明显。需要进一步的定性和定量研究来探索这些发现。

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Accessing breast cancer care in a protracted conflict: Qualitative exploration of the perspectives of women with breast cancer in northwest Syria.在持久冲突中获取乳腺癌护理:对叙利亚西北部乳腺癌妇女观点的定性探索。
Soc Sci Med. 2024 Nov;361:117364. doi: 10.1016/j.socscimed.2024.117364. Epub 2024 Sep 21.
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Barriers to access to cancer care for patients from the conflict-affected region of the Nagorno-Karabakh Republic: A qualitative study.纳戈尔诺-卡拉巴赫共和国冲突影响地区患者获得癌症护理的障碍:一项定性研究。
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J Clin Oncol. 2024 Jul 10;42(20):2456-2487. doi: 10.1200/JCO.24.00541. Epub 2024 May 16.
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Supporting Communities in Humanitarian Crises with Acupuncture and Integrative Medicine A Perspective.从针灸和整合医学角度看在人道主义危机中支持社区
Med Acupunct. 2023 Aug 1;35(4):159-162. doi: 10.1089/acu.2023.0012. Epub 2023 Aug 14.
5
Integrative Oncology Care of Symptoms of Anxiety and Depression in Adults With Cancer: Society for Integrative Oncology-ASCO Guideline.癌症成人焦虑和抑郁症状的整合肿瘤学照护:整合肿瘤学协会-美国临床肿瘤学会指南。
J Clin Oncol. 2023 Oct 1;41(28):4562-4591. doi: 10.1200/JCO.23.00857. Epub 2023 Aug 15.
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Acupuncture and integrative oncology for taxane-induced peripheral neuropathy: a randomized multicentered study.针刺与综合肿瘤学治疗紫杉烷引起的周围神经病变:一项随机多中心研究。
Int J Gynecol Cancer. 2023 May 1;33(5):792-801. doi: 10.1136/ijgc-2022-004004.
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Integrative Medicine for Pain Management in Oncology: Society for Integrative Oncology-ASCO Guideline.肿瘤学中的疼痛管理整合医学:肿瘤整合医学学会-美国临床肿瘤学会指南。
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