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[Retracted] MEG3/miR‑21 axis affects cell mobility by suppressing epithelial‑mesenchymal transition in gastric cancer.[已撤回]MEG3/miR-21轴通过抑制胃癌中的上皮-间质转化来影响细胞迁移。
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[已撤回]MEG3/miR-21轴通过抑制胃癌中的上皮-间质转化来影响细胞迁移。

[Retracted] MEG3/miR‑21 axis affects cell mobility by suppressing epithelial‑mesenchymal transition in gastric cancer.

作者信息

Xu Gang, Meng Lei, Yuan Dawei, Li Kang, Zhang Yong, Dang Chengxue, Zhu Kun

机构信息

Department of Surgical Oncology, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi 710061, P.R. China.

出版信息

Oncol Rep. 2024 Oct;52(4). doi: 10.3892/or.2024.8799. Epub 2024 Aug 19.

DOI:10.3892/or.2024.8799
PMID:39155871
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11358672/
Abstract

Following the publication of this paper, it was drawn to the Editor's attention by a concerned reader that certain of the Transwell cell invasion assay data shown in Fig. 2B on p. 42 and the immunofluorescence data shown in Fig. 4D on p. 44 were strikingly similar to data appearing in other articles written by different authors at different research institutes that were submitted to different journals at around the same time. Moreover, a further investigation of this paper undertaken by the Editorial Office identified a large number of overlapping data panels comparing the Transwell cell migration and invasion assay data and the scratch‑wound assay data both within and between Figs. 2 and 3, where data which were intended to have shown the results from differently performed experiments had apparently been derived from the same original source, including an overlapping section of data within the 'MEG3+mimic' panel in Fig. 3G that would be difficult to attribute to pure chance. Owing to the fact that the contentious data in the above article had already been submitted for publication at around the same time as its submission to , and given an overall lack of confidence in the presented data, the Editor has decided that this paper should be retracted from the Journal. The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused. [Oncology Reports 40: 39‑48, 2018; DOI: 10.3892/or.2018.6424].

摘要

在本文发表后,一位关注此事的读者提醒编辑注意,第42页图2B所示的某些Transwell细胞侵袭试验数据以及第44页图4D所示的免疫荧光数据,与不同研究机构的不同作者在大约同一时间提交给不同期刊的其他文章中出现的数据惊人地相似。此外,编辑部对本文进行的进一步调查发现,在图2和图3内以及图2和图3之间,比较Transwell细胞迁移和侵袭试验数据以及划痕试验数据的大量数据面板存在重叠,其中旨在显示不同实验结果的数据显然来自同一原始来源,包括图3G中“MEG3+模拟物”面板内的数据重叠部分,这很难归因于纯粹的巧合。由于上述文章中的有争议数据在提交给本期刊的同时已提交发表,且对所呈现的数据总体缺乏信心,编辑决定从本期刊撤回本文。已要求作者对这些问题作出解释,但编辑部未收到答复。编辑就由此造成的任何不便向读者致歉。[《肿瘤学报道》40: 39 - 48, 2018; DOI: 10.3892/or.2018.6424]