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[在使用药物依从性辅助工具(MCA)纳入药物调理服务的多药治疗患者中根据肾功能进行剂量调整]

[Dose adjustment according to renal function in a polymedicated patient included in the medication reconditioning service using medication compliance aids (MCA)].

作者信息

Barris Blundell Damià, Mousavi Homa

机构信息

Farmacéutico comunitario. Farmacia Zarzuelo, Benalmádena (Málaga). España.

出版信息

Farm Comunitarios. 2024 Mar 19;16(2):37-42. doi: 10.33620/FC.2173-9218.(2024).10. eCollection 2024 Apr 15.

DOI:10.33620/FC.2173-9218.(2024).10
PMID:39156027
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11328326/
Abstract

78-year-old patient, polymedicated and enrolled in the medication compliance aids service. When she went to pick up her medication, she informed us that for a few months she has been suffering from fatigue, weakness, dizziness and confusion. A medication review is performed, focused on the dosage of renal metabolism or elimination medications, based on the patient's estimated Glomerular Filtration Rate (eGFR). A referral was made to the Primary Care Physician (PCP) through a report, in which the dose reduction of losartan and manidipine was recommended according to the patient's eGFR. The PCP reduced the dose of antihypertensives. A follow-up of the case was carried out, which allowed to observe that the patient stopped presenting the symptoms initially described.

摘要

78岁患者,服用多种药物,参加了药物依从性辅助服务。当她去取药时,告知我们几个月来一直感到疲劳、虚弱、头晕和困惑。根据患者的估算肾小球滤过率(eGFR)进行了药物审查,重点关注肾脏代谢或排泄药物的剂量。通过一份报告将患者转诊给初级保健医生(PCP),其中建议根据患者的eGFR降低氯沙坦和马尼地平的剂量。初级保健医生降低了抗高血压药物的剂量。对该病例进行了随访,发现患者不再出现最初描述的症状。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/64df/11328326/131e712302e0/FC16-02-05_gf01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/64df/11328326/131e712302e0/FC16-02-05_gf01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/64df/11328326/131e712302e0/FC16-02-05_gf01.jpg

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本文引用的文献

1
Effectiveness of a drug dosing service provided by community pharmacists in polymedicated elderly patients with renal impairment--a comparative study.社区药师提供的药物剂量服务在肾功能损害的老年多药治疗患者中的效果 - 一项比较研究。
BMC Fam Pract. 2013 Jul 13;14:96. doi: 10.1186/1471-2296-14-96.