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术前辅助治疗期间个体化预康复对食管癌患者肌肉减少症的预防及运动耐量的维持:一例报告

Prevention of Sarcopenia and Maintenance of Exercise Tolerance by Individualized Prehabilitation in a Patient With Esophageal Cancer During Preoperative Adjuvant Therapy: A Case Report.

作者信息

Sakamoto Ririko, Okura Kazuki, Nagaki Yushi, Wakita Akiyuki, Sato Yusuke

机构信息

Department of Rehabilitation Medicine, Akita University Hospital, Akita, JPN.

Department of Esophageal Surgery, Akita University Hospital, Akita, JPN.

出版信息

Cureus. 2024 Jul 16;16(7):e64633. doi: 10.7759/cureus.64633. eCollection 2024 Jul.

Abstract

Preoperative adjuvant therapy for esophageal cancer increases sarcopenia and decreases exercise tolerance, which are risk factors for postoperative pneumonia. Preoperative rehabilitation for patients undergoing esophagectomy effectively reduces the incidence of postoperative pneumonia. Therefore, the risk factors should be optimized by preoperative rehabilitation. Our patient had several risk factors for postoperative pneumonia, including low exercise tolerance, presarcopenia, and low respiratory muscle strength. However, because of the patient's advanced age, multiple comorbidities, and poor nutritional status, we struggled to determine the appropriate exercise intensity. Furthermore, there was a concern that chemotherapy-related adverse events could prevent adequate exercise from being performed. However, with individualized measures such as adjustable exercise intensity settings based on treatment status and nutritional management through multidisciplinary collaboration, it was possible to prevent sarcopenia and maintain exercise tolerance during preoperative adjuvant therapy. Individualized support in preoperative rehabilitation was suggested to contribute to the prevention of sarcopenia and maintenance of exercise tolerance during preoperative adjuvant therapy.

摘要

食管癌术前辅助治疗会增加肌肉减少症并降低运动耐量,而这两者都是术后肺炎的危险因素。对接受食管切除术的患者进行术前康复可有效降低术后肺炎的发生率。因此,应通过术前康复来优化这些危险因素。我们的患者有多个术后肺炎的危险因素,包括运动耐量低、肌肉减少症前期和呼吸肌力量低。然而,由于患者年龄较大、合并多种疾病且营养状况较差,我们难以确定合适的运动强度。此外,还担心化疗相关的不良事件会妨碍进行充分的运动。然而,通过采取个体化措施,如根据治疗状态调整运动强度设置以及通过多学科协作进行营养管理,在术前辅助治疗期间有可能预防肌肉减少症并维持运动耐量。建议术前康复中的个体化支持有助于在术前辅助治疗期间预防肌肉减少症并维持运动耐量。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0ca6/11328822/0de1cf0df870/cureus-0016-00000064633-i01.jpg

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