Pooniya Vishal, Chandra Abhilash, Rao S Namrata, Singh Amit K, Malhotra Kiran P
Department of Nephrology, Dr. Ram Manohar Lohia Institute of Medical Sciences, Gomti Nagar, Lucknow, Uttar Pradesh, India.
Department of Pathology, Dr. Ram Manohar Lohia Institute of Medical Sciences, Gomti Nagar, Lucknow, Uttar Pradesh, India.
Indian J Nephrol. 2024 Jul-Aug;34(4):395-397. doi: 10.25259/IJN_9_21. Epub 2024 Jul 20.
Ammonia may cause poisoning due to inhalation or ingestion. Renal involvement in ammonia poisoning has been reported only once. A 30-year-old male working in an ice factory was accidentally exposed to liquid ammonia from a leaking hose, following which he had burns over his face and neck and severe abdominal pain. On day 2, he had deranged renal function, which was progressive. He was referred to us due to persistent renal dysfunction. A kidney biopsy was performed due to slow recovery of renal failure, which was suggestive of acute tubular necrosis. He was managed conservatively and showed gradual improvement over 12 days of his hospital stay. Renal functions normalized after 14 days of discharge. This case highlights the occurrence of renal involvement in ammonia poisoning.
氨可因吸入或摄入而导致中毒。关于氨中毒时肾脏受累的报道仅有一例。一名在制冰厂工作的30岁男性意外接触到从泄漏软管中喷出的液态氨,随后他的面部和颈部出现烧伤,并伴有严重腹痛。第2天,他出现肾功能紊乱,且呈进行性发展。由于肾功能持续异常,他被转诊至我们医院。因肾衰竭恢复缓慢,故进行了肾活检,结果提示急性肾小管坏死。对他进行了保守治疗,在住院12天期间病情逐渐好转。出院14天后肾功能恢复正常。该病例突出了氨中毒时肾脏受累的情况。