Medina R, Michelson E L
Cardiovasc Clin. 1985;16(1):177-213.
Great advances in pacemaker technology have produced devices capable of a vast array of physiologic adaptations formerly unimaginable, opening new possibilities in the pacemaker treatment of almost all rhythm disturbances. Nearly all units in use today are of the inhibited type, except for some antitachycardia applications. The AV-sequential mode (DVI) allows for preservation of AV synchrony, and the universal pacemaker (DDD) allows for a more physiologic response to a range of atrial rates. Programmability of numerous parameters has added a new dimension of adaptability to a variety of changing physiologic needs and pacemaker performance patterns, eliminating the need for surgical revision in many cases. The standard power source of today's pacemaker is the lithium chemistry cell, and the 5-year pacemaker is a reality, with 10 to 15 years of longevity distinctly possible in the near future. Almost all pacemakers use the transvenous route for access to the heart; new positive-fixation electrodes reduce displacement to a minimum; and new polyurethane or silicone-rubber leads have greatly simplified the techniques for implantation. Bipolar pacing systems are preferred, to avoid the oversensing of skeletal muscle interference--a problem that is especially important in triggered systems such as those used for antitachycardia applications. Threshold measurements are performed in millivolts at the time of implantation of most constant-voltage units, and current threshold measurements are useful for troubleshooting when failure to capture exists. Sensitivity parameters should be adjusted to sense the intracardiac signal; its amplitude should be determined in all cases, and measurement of the slew rate is useful when the amplitude is marginal. Recording of AV and VA conduction characteristics should be part of the routine implanting procedure, especially when simple blood pressure measurement during ventricular pacing indicates that this modality will be poorly tolerated and, therefore, implantation of a dual-chamber unit is contemplated. Different modalities of pacemaker malfunction have been reviewed, including the "cross-talk" phenomenon encountered with dual-chamber pacing. With the introduction of newer techniques, a host of pacemaker-mediated tachycardias have appeared, notably the "endless-loop" tachycardia of DDD pacemakers. This and other electrophysiologic phenomena of normal pacemaker function are bound to multiply as technology becomes more complex, but they should not be a problem if the programmable parameters are adapted to the electrophysiology of each particular patient.(ABSTRACT TRUNCATED AT 400 WORDS)
起搏器技术取得了巨大进展,生产出了能够实现大量以前难以想象的生理适应性的设备,为几乎所有心律失常的起搏器治疗开辟了新的可能性。除了一些抗心动过速应用外,如今几乎所有使用的起搏器都是抑制型的。房室顺序模式(DVI)可保持房室同步,通用起搏器(DDD)可对一系列心房率做出更生理性的反应。众多参数的可编程性为适应各种不断变化的生理需求和起搏器性能模式增添了新的维度,在许多情况下无需进行手术修正。当今起搏器的标准电源是锂化学电池,5年期起搏器已成为现实,在不久的将来,使用寿命达到10至15年明显是可能的。几乎所有起搏器都采用经静脉途径进入心脏;新型主动固定电极将移位降至最低;新型聚氨酯或硅橡胶导线大大简化了植入技术。首选双极起搏系统,以避免过度感知骨骼肌干扰——这一问题在诸如用于抗心动过速应用的触发系统中尤为重要。在植入大多数恒压装置时,阈值测量以毫伏为单位进行,当存在夺获失败时,电流阈值测量有助于故障排查。应调整灵敏度参数以感知心内信号;在所有情况下都应确定其幅度,当幅度处于临界值时,测量上升速率是有用的。记录房室和室房传导特性应作为常规植入程序的一部分,尤其是当心室起搏期间简单的血压测量表明这种方式耐受性差,因此考虑植入双腔起搏器时。已对起搏器故障的不同模式进行了综述,包括双腔起搏时遇到的“串扰”现象。随着更新技术的引入,出现了许多起搏器介导的心动过速,尤其是DDD起搏器的“无休止环”心动过速。随着技术变得更加复杂,正常起搏器功能的这种及其他电生理现象必然会增加,但如果可编程参数能适应每个特定患者的电生理学,它们就不应成为问题。(摘要截取自400字)