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卵圆孔未闭导致合并平卧呼吸-直立性低氧血症综合征及中风

PFO Leading to Concomitant Platypnea-Orthodeoxia Syndrome and Stroke.

作者信息

Mancini Benjamin, Kaleta Francois, Zimmerman Eric, Daflissio Gianna, Muallem Samer, Chan Eric, Kozak Mark, Wilson Ryan

机构信息

Penn State College of Medicine, Hershey, Pennsylvania, USA.

Penn State Heart and Vascular Institute, Hershey, Pennsylvania, USA.

出版信息

JACC Case Rep. 2024 Aug 7;29(15):102439. doi: 10.1016/j.jaccas.2024.102439.

DOI:10.1016/j.jaccas.2024.102439
PMID:39157570
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11328783/
Abstract

Platypnea-orthodeoxia syndrome is a rare entity seen in patients with patent foramen ovale, characterized by dyspnea and arterial desaturation in the upright position. We describe a case of a patient who presented with cryptogenic stroke, evidence of right-to-left interatrial shunting, and refractory hypoxemia necessitating closure of his patent foramen ovale.

摘要

平卧呼吸-直立性低氧血症综合征是一种在卵圆孔未闭患者中罕见的病症，其特征为直立位时出现呼吸困难和动脉血氧饱和度降低。我们描述了一例患者，该患者表现为隐源性卒中、存在右向左心房分流的证据以及难治性低氧血症，需要关闭其卵圆孔未闭。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/702c/11328783/c5697772d993/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/702c/11328783/19ad79f33158/ga1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/702c/11328783/630f91412132/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/702c/11328783/3a195ff61111/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/702c/11328783/c5697772d993/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/702c/11328783/19ad79f33158/ga1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/702c/11328783/630f91412132/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/702c/11328783/3a195ff61111/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/702c/11328783/c5697772d993/gr3.jpg

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JACC Case Rep. 2024 Aug 7;29(15):102439. doi: 10.1016/j.jaccas.2024.102439.
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本文引用的文献

1
SCAI Guidelines for the Management of Patent Foramen Ovale.SCAI卵圆孔未闭管理指南。
J Soc Cardiovasc Angiogr Interv. 2022 May 19;1(4):100039. doi: 10.1016/j.jscai.2022.100039. eCollection 2022 Jul-Aug.
2
Platypnea orthodeoxia syndrome after recent stroke: a case report of a sandwiched right atrium.近期卒中后出现的平卧呼吸-直立性低氧血症综合征：一例右心房夹在中间的病例报告
Eur Heart J Case Rep. 2022 Jul 5;6(7):ytac275. doi: 10.1093/ehjcr/ytac275. eCollection 2022 Jul.
3
Platypnea-Orthodeoxia Syndrome With Normal Right Heart Pressures in an Octogenarian.
一位八旬老人患有右心压力正常的平卧呼吸-直立性低氧血症综合征。
JACC Case Rep. 2020 Feb 19;2(2):324-325. doi: 10.1016/j.jaccas.2019.12.020. eCollection 2020 Feb.
4
Persistent pathology of the patent foramen ovale: a review of the literature.持续性卵圆孔未闭的病理学：文献复习。
Med J Aust. 2021 Jul;215(2):89-93. doi: 10.5694/mja2.51141. Epub 2021 Jul 4.
5
The multiple dimensions of Platypnea-Orthodeoxia syndrome: A review.平卧呼吸-直立性低氧血症综合征的多维度研究：综述
Respir Med. 2017 Aug;129:31-38. doi: 10.1016/j.rmed.2017.05.016. Epub 2017 May 31.
6
Cryptogenic Stroke: Making the Management Less Cryptic.隐源性卒中：让管理不再神秘。
Cardiol Rev. 2016 Jul-Aug;24(4):153-7. doi: 10.1097/CRD.0000000000000073.
7
Unexplained dyspnea in an old patient with recurrent stroke: platypnea-orthodeoxia syndrome and evidence of patent foramen ovale.老年复发性卒中患者不明原因呼吸困难：屏气-直立性低氧血症综合征和卵圆孔未闭证据。
Neurol Sci. 2010 Feb;31(1):93-4. doi: 10.1007/s10072-009-0169-9. Epub 2009 Oct 30.
8
Mechanisms of platypnea-orthodeoxia: what causes water to flow uphill?平卧呼吸-直立性低氧血症的机制：是什么导致水向上流动？
Circulation. 2002 Feb 12;105(6):e47.