Nerea Acuña Elvira, Óscar Bailón Fernández
Licenciada en Farmacia. Doctora en Ciencias de la Salud. Farmacéutica comunitaria en Lanzarote Farmacia España.
Fisioterapeuta en ASEPEYO Asepeyo España.
Farm Comunitarios. 2023 Apr 10;15(3):43-45. doi: 10.33620/FC.2173-9218.(2023).20. eCollection 2023 Jul 15.
A 34-year-old man who presents recurrent urological infections treated with different antibiotics as a consequence of urethral stricture, has undergone several surgeries since 2018. Some episodes of infection present with very intense pain and others are asymptomatic. In December 2021, high fever, very intense headache and muscle pain appeared for the first time, for which reason the symptoms were confused with COVID-19. When these symptoms appeared, the patient had been treated for 8 days with Trimethoprim/sulfamethoxazole 160/800 mg. After negative COVID-19 tests, they decide to hospitalize the patient in urology and determine that the symptoms are due to urological infection. He was also diagnosed with myocarditis and peripheral neuropathy. During the following months, the patient returns to have positive urine cultures for different bacteria and is treated with other antibiotics. In May 2022, after positive for Escherichia coli, he was prescribed Trimethoprim/sulfamethoxazole 160/800 mg, 2 days after starting treatment he was hospitalized with a very high fever, severe headache, and pain in the lower back and in the extremities that prevented him from moving. He is referred to traumatology and is diagnosed with low back pain. After the second admission, the patient discusses the case with his trusted pharmacist who knows his clinical history from the beginning and by conducting a study it is detected that there is a possibility that the acute symptoms are due to an adverse effect of trimethoprim/sulfamethoxazole 160/800 mg. The pharmacist notifies the patient of her suspicion that she transfers him to the doctors who treat him. Information on possible intolerance/allergy is included in the patient's clinical history.
一名34岁男性因尿道狭窄反复接受不同抗生素治疗泌尿系统感染，自2018年以来已接受多次手术。有些感染发作时疼痛非常剧烈，有些则无症状。2021年12月，首次出现高热、剧烈头痛和肌肉疼痛，因此这些症状被误诊为新冠肺炎。出现这些症状时，患者已服用甲氧苄啶/磺胺甲恶唑160/800毫克治疗8天。新冠肺炎检测呈阴性后，他们决定将患者收治到泌尿外科，并确定症状是由泌尿系统感染引起的。他还被诊断出患有心肌炎和周围神经病变。在接下来的几个月里，患者的尿液培养多次出现不同细菌阳性，并接受了其他抗生素治疗。2022年5月，大肠杆菌检测呈阳性后，他被开了甲氧苄啶/磺胺甲恶唑160/800毫克，开始治疗两天后，他因高热、严重头痛以及下背部和四肢疼痛而住院，疼痛导致他无法活动。他被转诊至创伤科，被诊断为腰痛。第二次入院后，患者与了解其病史的信任药剂师讨论了该病例，通过研究发现急性症状有可能是由160/800毫克甲氧苄啶/磺胺甲恶唑的不良反应引起的。药剂师将她的怀疑告知患者，并将他转交给治疗他的医生。患者的临床病史中记录了可能的不耐受/过敏信息。
