Tinnirello Agata Angelita
Pathology Department, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Cytopathology. 2025 Jan;36(1):2-11. doi: 10.1111/cyt.13428. Epub 2024 Aug 19.
With multiple health care centres expanding and implementing remotely controlled technologies, the role of cytopathology laboratories will become crucial in optimizing collection and assessment of small biopsy specimens for diagnosis and personalized treatment. Cytopathology services provide rapid assessments of samples obtained from fine-needle aspirations and occasionally core needle biopsies (analysed by touch imprints). Over the past few decades, the cost barrier for hospitals, especially small ones, to support a cytopathologist or cytotechnologist for rapid on-site evaluation (ROSE) has been reduced by the introduction of computerized microscopes that allow cytopathologists to perform ROSE without being present at the satellite laboratory (i.e. remotely). Utilization of the cytotechnologist's experience in ROSE alongside these technologies made it possible to perform ROSE with telecytology (ROSE-TC), which positively impacts diagnosis and treatment and also lowers the cost of care. The satellite laboratories that successfully implemented ROSE-TC operate with experienced cytotechnologists who, working independently between the cytopathology laboratory and the biopsy suite, prepare the smears and stain the slides on site for the distant cytopathologists, who can evaluate the slides remotely (usually from their office) simply using the facility intranet. This article aims to encourage big and small centres to use senior-level cytotechnologists for both ROSE and ROSE-TC. This article also defines different types of ROSE, explains our institution's approach to ROSE procedures, and outlines some experience-driven considerations for successful ROSE-TC and its future evolution.
随着多个医疗保健中心不断扩大并采用远程控制技术，细胞病理学实验室在优化小活检标本的采集和评估以进行诊断和个性化治疗方面的作用将变得至关重要。细胞病理学服务可对细针穿刺获取的样本以及偶尔对粗针活检样本（通过触摸印片进行分析）进行快速评估。在过去几十年中，计算机化显微镜的引入降低了医院，尤其是小型医院配备细胞病理学家或细胞技术专家进行快速现场评估（ROSE）的成本障碍，这使得细胞病理学家无需亲临卫星实验室（即远程）即可进行ROSE。利用细胞技术专家在ROSE方面的经验以及这些技术，使得通过远程细胞病理学（ROSE-TC）进行ROSE成为可能，这对诊断和治疗产生了积极影响，同时也降低了护理成本。成功实施ROSE-TC的卫星实验室由经验丰富的细胞技术专家运作，他们在细胞病理学实验室和活检室之间独立工作，在现场为远程的细胞病理学家制备涂片并对玻片进行染色，远程的细胞病理学家只需使用机构内部网络就能（通常从他们的办公室）远程评估玻片。本文旨在鼓励大小中心使用高级细胞技术专家进行ROSE和ROSE-TC。本文还定义了不同类型的ROSE，解释了我们机构进行ROSE程序的方法，并概述了一些基于经验的成功实施ROSE-TC及其未来发展的考虑因素。
