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内淋巴囊神经鞘瘤模拟后半规管耳石症。

Intralabyrinthine Schwannoma Mimicking Posterior Canalithiasis.

机构信息

Department of Otorhinolaryngology Head & Neck Surgery and Audiology, Hearing and Balance Center, Rigshospitalet, University Hospital of Copenhagen, Copenhagen, Denmark.

University of Copenhagen, Faculty of Health and Medical Sciences,Copenhagen, Denmark.

出版信息

J Int Adv Otol. 2024 May 23;20(3):279-282. doi: 10.5152/iao.2024.231410.

Abstract

Intralabyrinthine schwannomas are a rare subgroup of vestibular schwannomas located within the membranous labyrinth of the inner ear and are known for their variable clinical presentations and symptoms. In the present study, we report on a patient with a persistent history of dizziness and positional vertigo, who was misdiagnosed with posterior canalithiasis. As hearing loss was not developed until late in the disease course, the patient was not properly diagnosed until magnetic resonance imaging revealed an intralabyrinthine schwannoma, which was not discovered on earlier imaging. In addition to the unusual clinical presentation, we describe the audio-vestibular profile of our patient. We suggest that a thorough vestibular evaluation, including caloric testing and a careful examination of the inner ear on imaging, is warranted in cases of treatment of refractory vertigo, even in patients where a diagnosis seems certain.

摘要

内淋巴囊神经鞘瘤是前庭神经鞘瘤的一个罕见亚型,位于内耳的膜迷路内,其临床表现和症状多样。本研究报告了一例持续性头晕和位置性眩晕患者,该患者被误诊为后半规管耳石症。由于听力损失直到疾病晚期才出现,因此直到磁共振成像显示内淋巴囊神经鞘瘤时,患者才得到正确诊断,而之前的影像学检查并未发现该肿瘤。除了不常见的临床表现外,我们还描述了我们患者的听前庭特征。我们建议,对于难治性眩晕的治疗,即使在诊断似乎明确的情况下,也应进行彻底的前庭评估,包括冷热试验和仔细的内耳影像学检查。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b10b/11232092/bdf6efa18e63/jiao-20-3-279_f001.jpg

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本文引用的文献

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Current imaging tools for vestibular schwannoma.前庭神经鞘瘤的现有影像学检查手段。
Curr Opin Otolaryngol Head Neck Surg. 2020 Oct;28(5):302-307. doi: 10.1097/MOO.0000000000000647.
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Different clinical presentation of intralabyrinthine schwannomas - a systematic review.不同部位内听神经鞘瘤的临床表现-系统综述。
Braz J Otorhinolaryngol. 2019 Jan-Feb;85(1):111-120. doi: 10.1016/j.bjorl.2018.05.007. Epub 2018 Jun 21.
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Intralabyrinthine schwannomas: imaging diagnosis and classification.内淋巴囊神经鞘瘤:影像学诊断与分类。
AJNR Am J Neuroradiol. 2012 Jan;33(1):104-9. doi: 10.3174/ajnr.A2712. Epub 2011 Dec 8.

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