Ohio University Heritage College of Osteopathic Medicine.
Department of Orthopaedics, The Ohio State University Wexner Medical Center, Columbus, OH, USA; College of Medicine, The Ohio State University Wexner Medical Center, Columbus, OH, USA.
J Biomech. 2024 Sep;174:112264. doi: 10.1016/j.jbiomech.2024.112264. Epub 2024 Aug 8.
The purpose of this study was (1) to determine the utility of shear wave elastography as a predictor for the mechanical failure of superficial knee ligaments and (2) to determine the viability of shear wave elastography to assess injury risk potential. Our hypothesis was that shear wave elastography measurements of the anterolateral ligament and medial collateral ligament would directly correlate with the material properties and the mechanical failure of the ligament, serving as a prognostic measurement for injury risk. 8 cadaveric specimens were acquired, and tissue stiffness for the anterolateral ligament and medial collateral ligament were evaluated with shear wave elastography. The anterolateral ligament and medial collateral ligament were dissected and isolated for unilateral mechanical failure testing. Ultimate failure testing was performed at 100 % strain per second after 50 cycles of 3 % strain viscoelastic conditioning. Each specimen was assessed for load, displacement, and surface strain throughout failure testing. Rate of force, rate of strain development, and Young's modulus were calculated from these variables. Shear wave elastography stiffness for the anterolateral ligament correlated with mean longitudinal anterolateral ligament strain at failure (R = 0.853; P<0.05). Medial collateral ligament shear wave elastography calculated modulus was significantly greater than the anterolateral ligament shear wave elastography calculated modulus. Shear wave elastography currently offers limited reliability in the prediction of mechanical performance of superficial knee ligaments. The utility of shear wave elastography assessment for injury risk potential remains undetermined.
（1）确定剪切波弹性成像作为预测浅表膝关节韧带力学失效的效用；（2）确定剪切波弹性成像评估损伤风险的潜力。我们的假设是，前外侧韧带和内侧副韧带的剪切波弹性成像测量值将与韧带的材料特性和力学失效直接相关，作为损伤风险的预测性测量。本研究共获得了 8 个尸体标本，并使用剪切波弹性成像评估了前外侧韧带和内侧副韧带的组织硬度。对前外侧韧带和内侧副韧带进行解剖和分离，用于单侧力学失效测试。在 50 次 3%应变粘弹性预适应循环后，以 100%应变/秒的速度进行最终失效测试。在整个失效测试过程中，对每个标本的负载、位移和表面应变进行评估。从这些变量中计算出力的速率、应变发展的速率和杨氏模量。前外侧韧带的剪切波弹性成像硬度与失效时前外侧韧带的平均纵向应变相关（R=0.853；P<0.05）。内侧副韧带的剪切波弹性成像计算的模量明显大于前外侧韧带的剪切波弹性成像计算的模量。剪切波弹性成像目前在预测浅表膝关节韧带的力学性能方面提供了有限的可靠性。剪切波弹性成像评估损伤风险的潜力仍不确定。
