Department of Internal Medicine, SUNY Upstate Medical University.
Department of Internal Medicine, Western Michigan University Homer Stryker M.D. School of Medicine.
Curr Probl Cardiol. 2024 Nov;49(11):102805. doi: 10.1016/j.cpcardiol.2024.102805. Epub 2024 Aug 17.
Heart failure continues to pose a significant burden in terms of morbidity, mortality, and healthcare costs worldwide despite the implementation of guideline-directed medical therapy. Addressing this challenge and improving clinical outcomes for this patient population remains an urgent priority. Recognizing the limitations in current medical approaches and exploring strategies to overcome these limitations are crucial steps toward improving future outcomes. Various device-based interventions, such as Cardiac Resynchronization Therapy devices and Left Ventricular Assist Devices, have demonstrated notable benefits for individuals with heart failure. Our review is aimed at summarizing the ongoing research into new device therapies for heart failure, emphasizing their potential to overcome the current challenges in treatment. By utilizing Clinicaltrials.gov, an online repository, we conducted a comprehensive search for trials investigating emerging device therapies for patients dealing with heart failure.
尽管实施了指南指导的医学治疗,但心力衰竭在全球范围内仍在很大程度上给发病率、死亡率和医疗保健成本带来负担。解决这一挑战并改善这一患者群体的临床结果仍然是当务之急。认识到目前医疗方法的局限性并探索克服这些局限性的策略是改善未来结果的关键步骤。各种基于设备的干预措施,如心脏再同步治疗设备和左心室辅助设备,已经为心力衰竭患者带来了显著的益处。我们的综述旨在总结心力衰竭新设备治疗的研究进展,强调它们有潜力克服目前治疗中的挑战。我们利用 Clinicaltrials.gov,一个在线数据库,对正在研究心力衰竭患者新兴设备治疗的试验进行了全面搜索。