Pathology and Lab Medicine, AIIMS Raipur, Raipur, Chhattisgarh, India.
Pathology, AIIMS Raipur, Raipur, Chhattisgarh, India
BMJ Case Rep. 2024 Aug 19;17(8):e258652. doi: 10.1136/bcr-2023-258652.
A female, in her 60s, presented with pain and swelling of the right eye for 3 years. The radiological work-up revealed an extraconal solid-cystic orbital tumour suggestive of an epidermoid cyst. The patient underwent supraorbital craniotomy with a gross total excision of the tumour. An intraoperative diagnosis was sought, which on both squash smear and frozen section showed features of craniopharyngioma (CP), later confirmed on paraffin sections and immunohistochemistry. The orbit is a very rare site for ectopic CP, with only two cases reported in the literature. Many theories have been proposed to explain the occurrence of CP at ectopic sites. This report aims to provide insight into the different hypotheses of the pathogenesis of ectopic CP through a review of the literature.
一位 60 多岁的女性，因右眼疼痛和肿胀 3 年来就诊。影像学检查显示眶外实性囊性肿瘤，提示表皮样囊肿。患者接受了经眶上颅骨切开术，肿瘤被完全切除。术中寻求诊断，在压碎涂片和冷冻切片上均显示颅咽管瘤（CP）的特征，随后在石蜡切片和免疫组织化学上得到证实。眼眶是颅咽管瘤异位的非常罕见部位，文献中仅报道了两例。许多理论已经提出，以解释异位部位 CP 的发生。本报告旨在通过文献复习，深入了解异位 CP 发病机制的不同假说。
