Department of Research, Kharadar General Hospital, Karachi, Pakistan.
Department of Paediatrics, Kharadar General Hospital, Karachi, Pakistan.
J Pak Med Assoc. 2024 Aug;74(8):1518-1520. doi: 10.47391/JPMA.11385.
Quintuplet pregnancies are associated with significant perinatal morbidity and mortality. The spontaneous quintuplets are a rare occurrence, and the survival is extremely rare. The first quintuplets known to survive infancy to adulthood were the Dionne Quintuplets, born in 1934. Kharadar quintuplets born in 2006, in Karachi Pakistan, were the first set of quintuplets who were born alive and reached their adolescence. A 30-year old women, presented at Kharadar General Hospital (KGH) during the 28th week of gestation for pregnancy evaluation. She was diagnosed with a quintuplet pregnancy with no gross foetal abnormality on ultrasound abdomen. The patient had premature rupture of membrane at 30th week of gestation, and emergency caesarean section was performed. All five quints were born alive, had normal APGAR scores, were premature, and had low birth weight. After birth, all quints were immediately shifted to the neonatal intensive care unit. After a 10 day hospital stay, all quints were discharged. In 2023, all quints celebrated their 17th Birthday.
五胞胎妊娠与围产期发病率和死亡率显著相关。自发性五胞胎妊娠较为罕见,存活下来的更是极其罕见。已知最早存活至成年的五胞胎是 1934 年出生的 Dionne 五胞胎。2006 年,在巴基斯坦卡拉奇的 Kharadar,五胞胎出生,他们是第一组存活并进入青春期的五胞胎。一名 30 岁的妇女在妊娠 28 周时到 Kharadar 综合医院(KGH)进行妊娠评估。她被诊断为五胞胎妊娠,腹部超声检查未见明显胎儿异常。患者在妊娠 30 周时胎膜早破,行紧急剖宫产术。五名婴儿均存活,阿普加评分正常,早产且出生体重低。分娩后,所有五胞胎立即被转移到新生儿重症监护病房。住院 10 天后,所有五胞胎均出院。2023 年,所有五胞胎庆祝了他们的 17 岁生日。