Li Xin, Li Wanghong, Liu Chen, Xu Kai, Yi Chao, Tang Jintian, Jia Zhiying, Li Xinxia, Zhou Yong, Wang Boqing
Department of Hepatopancreatobiliary Surgery, The Affiliated Tumor Hospital of Xinjiang Medical University, Urumqi, Xinjiang Uygur Autonomous Region 830011, P.R. China.
Department of Ultrasound, Affiliated Tumor Hospital of Xinjiang Medical University, Urumqi, Xinjiang Uygur Autonomous Region 830011, P.R. China.
Exp Ther Med. 2024 Aug 2;28(4):386. doi: 10.3892/etm.2024.12675. eCollection 2024 Oct.
Angiomyxoma (AM) occurs almost exclusively in the soft tissues of the pelvic and perineal regions. AM is a highly uncommon condition that can be easily misdiagnosed when it is present in other regions of the body. The current study presents a case in which AM of the liver coexisted with focal nodular hyperplasia (FNH). A 56-year-old woman presented with two space-occupying lesions of the liver without any other clinical symptoms, and it was not easy to definitively diagnose the two intrahepatic lesions by imaging examinations. Due to the low incidence of AM in the liver, precise and clear clinical information on the condition is still unavailable, and the lesion was initially misdiagnosed as other hepatic tumors preoperatively. Once a tumor resection had been performed, a histopathological examination revealed that the microscopic features of the lesions were consistent with those of AM and FNH. The patient was followed up for 1 year, and no recurrence or metastasis was found. Surgical excision is an effective treatment for AM, and long-term follow-up is essential due to the risk of recurrence. The joint presentation of AM and FNH is rare in clinical practice, and although FNH of the liver is commonly reported, the difficulty of diagnosis increases when both conditions occur at the same time. Therefore, it is necessary to assist clinicians in making informed decisions regarding diagnosis and treatment.
血管黏液瘤（AM）几乎仅发生于盆腔和会阴区域的软组织。AM是一种极为罕见的疾病，当其出现在身体其他部位时很容易被误诊。本研究报告了一例肝脏血管黏液瘤与局灶性结节性增生（FNH）共存的病例。一名56岁女性肝脏出现两个占位性病变，无任何其他临床症状，通过影像学检查难以明确诊断这两个肝内病变。由于肝脏AM发病率低，目前仍缺乏关于该病精确且明确的临床信息，该病变术前最初被误诊为其他肝脏肿瘤。肿瘤切除术后，组织病理学检查显示病变的微观特征与AM和FNH相符。对患者进行了1年的随访，未发现复发或转移。手术切除是治疗AM的有效方法，鉴于存在复发风险，长期随访至关重要。AM和FNH同时出现的情况在临床实践中很少见，虽然肝脏FNH较为常见，但两者同时发生时诊断难度增加。因此，有必要协助临床医生做出关于诊断和治疗的明智决策。
