Perera Dinan, Rana Khizar, Caltabiano Carmelo, Patel Sandy, Selva Dinesh
Department of Ophthalmology and Visual Sciences, University of Adelaide, North Terrace, Adelaide, South Australia, Australia.
South Australian Institute of Ophthalmology, Royal Adelaide Hospital, Adelaide, South Australia, Australia.
Ophthalmic Plast Reconstr Surg. 2025;41(2):156-160. doi: 10.1097/IOP.0000000000002763. Epub 2024 Aug 20.
To report the normative dimensions of the infraorbital nerve on fat-suppressed gadolinium-enhanced MRI and correlate with patient demographics in an Australian cohort.
A retrospective review of patients who underwent coronal fat-suppressed gadolinium T1-weighted MRI from September 2021 to December 2023. One hundred sixty-eight orbits were included. The maximum diameter of the infraorbital nerve and the optic nerve sheath was measured. Orbits were excluded if there was unilateral or bilateral pathology of the infraorbital nerve or optic nerve sheath, incomplete MRI sequences, poor image quality, or indiscernible infraorbital nerve on radiological examination.
The mean age of participants was 58 ± 16 years, and 50% were females (n = 42). The mean normative measurements (mean ± standard deviation) on coronal T1-weighted imaging: optic nerve sheath, 5.08 ± 0.67 mm. On coronal fat-suppressed gadolinium T1-weighted imaging: infraorbital nerve, 0.89 ± 0.22mm. No significant differences were found between male or female participants in both the infraorbital nerve ( p = 0.757) or optic nerve sheath ( p = 0.646). There was no significant correlation between age and mean diameter of the infraorbital nerve (r = 0.077, p = 0.320) or optic nerve sheath (r = 0.075, p = 0.336). Additionally, no significant difference was identified between the mean diameter of the infraorbital nerve ( p = 0.079) and optic nerve sheath ( p = 0.120) across age groups. The mean infraorbital nerve to optic nerve sheath ratio was 0.18 ± 0.00.
Normative dimensions of the infraorbital nerve may be used to identify enlargement in conditions such as IgG4-related ophthalmic disease and reactive lymphoid hyperplasia.
报告脂肪抑制钆增强磁共振成像（MRI）下眶下神经的正常尺寸，并与澳大利亚队列中的患者人口统计学数据相关联。
回顾性分析2021年9月至2023年12月期间接受冠状位脂肪抑制钆T1加权MRI检查的患者。共纳入168个眼眶。测量眶下神经和视神经鞘的最大直径。如果存在眶下神经或视神经鞘的单侧或双侧病变、MRI序列不完整、图像质量差或影像学检查中眶下神经不可辨认，则排除相应眼眶。
参与者的平均年龄为58±16岁，50%为女性（n = 42）。冠状位T1加权成像上的平均正常测量值（平均值±标准差）：视神经鞘，5.08±0.67mm。在冠状位脂肪抑制钆T1加权成像上：眶下神经，0.89±0.22mm。男性和女性参与者在眶下神经（p = 0.757）或视神经鞘（p = 0.646）方面均未发现显著差异。年龄与眶下神经平均直径（r = 0.077，p = 0.320）或视神经鞘（r = 0.075，p = 0.336）之间无显著相关性。此外，各年龄组之间眶下神经平均直径（p = 0.079）和视神经鞘平均直径（p = 0.120）无显著差异。眶下神经与视神经鞘的平均比值为0.18±0.00。
眶下神经的正常尺寸可用于识别IgG4相关眼病和反应性淋巴组织增生等疾病中的神经增粗情况。
