Frost C E, Forster D P
Rev Environ Health. 1985;5(2):135-49.
Iatrogenesis is classified into two broad types: direct and indirect. By indirect iatrogenesis is meant the accidental or deliberate misuse of prescribed medication. Deliberate indirect iatrogenesis is explored through an analysis of deliberate non-fatal self-poisoning. A statistically significant relationship, previously found, between deliberate non-fatal self-poisoning and the frequency of prescription of psychotropics is used to evaluate the economic consequences of self-poisoning to the hospital sector. In the decision to use or not to use a particular drug, the importance of risk-benefit analysis is stressed. This analysis is used to distinguish between a drug's safety and efficacy. In general, no one criterion should be used to choose between alternative drugs. Finally, some policy implications of the analysis for psychotropic prescriptions are considered.
直接医源性疾病和间接医源性疾病。间接医源性疾病是指对处方药的意外或故意误用。通过对故意非致命性自我中毒的分析来探讨故意间接医源性疾病。先前发现的故意非致命性自我中毒与精神药物处方频率之间的统计学显著关系，被用于评估自我中毒对医院部门的经济后果。在决定使用或不使用某种特定药物时，强调了风险效益分析的重要性。这种分析用于区分药物的安全性和有效性。一般来说，不应仅依据单一标准在替代药物之间进行选择。最后，考虑了该分析对精神药物处方的一些政策影响。
