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[细菌性角膜炎:临床症状、病原体与治疗]

[Bacterial keratitis : Clinical aspects, pathogens and treatment].

作者信息

Hamon Loïc, Abu Dail Yaser, Daas Loay, Seitz Berthold

机构信息

Klinik für Augenheilkunde, Universitätsklinikum des Saarlandes, Kirrberger Straße, Geb. 22, 66421, Homburg/Saar, Deutschland.

出版信息

Ophthalmologie. 2024 Sep;121(9):769-782. doi: 10.1007/s00347-024-02102-9. Epub 2024 Aug 20.

Abstract

Bacterial infections are by far the most frequent cause of infectious keratitis in high-income countries. The clinical appearance can vary widely depending on the type and species of bacteria, ranging from small superficial infiltrates to necrotizing forms. The numerous classes of available antibiotics render the treatment scope diverse and complex, especially before the pathogen has been specified and the sensitivity to antibiotics has been tested. New therapeutic approaches to reduce bacterial virulence are in development. This CME article focuses on the clinical, diagnostic and therapeutic approaches to recognize and treat bacterial keratitis.

摘要

在高收入国家,细菌感染是感染性角膜炎最常见的病因。临床表现因细菌类型和种类的不同而有很大差异,从小的浅表浸润到坏死性病变都有。现有的众多类抗生素使治疗范围多样且复杂,尤其是在病原体尚未明确且抗生素敏感性尚未检测之前。降低细菌毒力的新治疗方法正在研发中。这篇继续医学教育文章重点介绍了识别和治疗细菌性角膜炎的临床、诊断和治疗方法。

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