Resident, Department of Neurology, Stanley Medical College and Hospital, Chennai, Tamil Nadu, India, Corresponding Author.
Assistant Professor, Department of Neurology, Stanley Medical College and Hospital, Chennai, Tamil Nadu, India.
J Assoc Physicians India. 2024 Aug;72(8):e31-e34. doi: 10.59556/japi.72.0585.
To study the clinical profile, etiology, and imaging features of subjects presenting with cerebral sinus venous thrombosis (CVST) and to correlate the clinical findings with radiological findings.
The study included 120 patients admitted with the diagnosis of CVST to Stanley Medical College and Hospital, Chennai. The study included patients of all age-groups presenting with cerebral venous thrombosis. The diagnosis was confirmed by imaging studies.
The mean age of presentation is 24.4, predominantly males. Headache (90.8%) was the most common presentation, followed by seizures (25%), and paresis (12%). The superior sagittal sinus (SSS) is the most common sinus involved, with multiple sinuses involved in 47% of patients. Magnetic resonance imaging (MRI) brain with magnetic resonance venography (MRV) is the investigation of choice. The most common risk factor for CSVT was alcohol intake, especially in males, and females, anemia, pregnancy, usage of oral contraceptive (OC) pills, and puerperium were the common risk factors. The causes of CSVT in this study were hyperhomocystenemia in 8%, anemia in 13%, and prothrombotic state in 6%.
Cerebral sinus venous thrombosis is a cause of stroke in young individuals. Even though uncommon, it is underdiagnosed because of its extremely varied clinical presentation. The correct diagnosis of CSVT relies on a high index of suspicion and the availability of advanced imaging like MRI with MR venography.
研究出现脑窦静脉血栓形成（CVST）的患者的临床特征、病因和影像学特征，并将临床发现与影像学发现相关联。
这项研究包括在钦奈斯坦利医学院和医院因 CVST 入院的 120 名患者。该研究包括所有年龄段出现脑静脉血栓形成的患者。通过影像学研究确诊。
发病的平均年龄为 24.4 岁，主要为男性。头痛（90.8%）是最常见的表现，其次是癫痫发作（25%）和瘫痪（12%）。最常受累的窦是上矢状窦（SSS），47%的患者有多个窦受累。首选的检查是磁共振成像（MRI）脑加磁共振静脉造影（MRV）。CSVT 的最常见危险因素是饮酒，尤其是男性和女性的危险因素，贫血、妊娠、口服避孕药（OC）的使用和产褥期也是常见的危险因素。本研究中 CSVT 的病因是高同型半胱氨酸血症占 8%、贫血占 13%和血栓形成前状态占 6%。
脑窦静脉血栓形成是年轻人中风的一个原因。尽管不常见，但由于其临床表现极其多样，因此诊断不足。CSVT 的正确诊断依赖于高度怀疑和先进影像学（如 MRI 加 MRV）的可用性。
