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Peripheral Ischemia Imprints Epigenetic Changes in Hematopoietic Stem Cells to Propagate Inflammation and Atherosclerosis.外周缺血在造血干细胞中留下表观遗传改变，从而引发炎症和动脉粥样硬化。
Arterioscler Thromb Vasc Biol. 2023 Jun;43(6):889-906. doi: 10.1161/ATVBAHA.123.318956. Epub 2023 Mar 9.
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Past history of obesity triggers persistent epigenetic changes in innate immunity and exacerbates neuroinflammation.肥胖既往史会引发先天性免疫中持续的表观遗传变化，并加剧神经炎症。
Science. 2023 Jan 6;379(6627):45-62. doi: 10.1126/science.abj8894. Epub 2023 Jan 5.
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Stroke-induced trained immunity spells bad news for the heart.

作者信息

Hajishengallis George, Chavakis Triantafyllos

机构信息

Department of Basic and Translational Sciences, Penn Dental Medicine, University of Pennsylvania, Philadelphia, PA, USA.

Institute for Clinical Chemistry and Laboratory Medicine, University Hospital and Faculty of Medicine, Technische Universität Dresden, Dresden, Germany.

出版信息

Cell Res. 2025 Feb;35(2):91-92. doi: 10.1038/s41422-024-01018-y.

DOI:10.1038/s41422-024-01018-y
PMID:39164387
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11770062/
Abstract
摘要