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比例风险模型在埃塞俄比亚东部接受 ART 治疗者社区抗逆转录病毒药物续药团体中的脱落及其预测因素

Proportional Hazards Model on Attrition and its Predictors in Community Antiretroviral Refill Groups among ART Users in Eastern Ethiopia.

机构信息

Department of Epidemiology and Biostatistics, School of Public Health, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia.

Department of Reproductive and Family Health, School of Public Health, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia.

出版信息

J Int Assoc Provid AIDS Care. 2024 Jan-Dec;23:23259582241273338. doi: 10.1177/23259582241273338.

DOI:10.1177/23259582241273338
PMID:39165103
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11339742/
Abstract

BACKGROUND

The HIV epidemic continues to be a major public health challenge worldwide, particularly in sub-Saharan African countries such as Ethiopia. Community-based antiretroviral refill groups are emerging as a patient-centered approach, but there is limited evidence. Therefore, this study aimed to assess attrition and predictors in community antiretroviral refill groups among ART users in Eastern Ethiopia.

METHODS

Institutional-based retrospective cohort study was conducted. Systematic random sampling techniques were used. Data were collected via Kobo Collect and exported to Stata. Statistically significant effects were assumed for a P-value < 0.05 at a confidence interval of 95%.

RESULTS

The incidence of attrition in community-based ART refill groups was 6.63 (95% CI: 5.78, 7.48) per 100 person-years. The median duration of months in CAGs from the start till the end of the follow-up period was 9 months (IQR = 24). Thus, recruitment level from health facilities, history of LTFU, and stage IV were statistically significant variables.

CONCLUSION

The findings of this study highlight the importance of improving the use of community antiretroviral groups in care. Healthcare programs can ultimately improve health outcomes for individuals living with HIV.

摘要

背景

艾滋病病毒(HIV)疫情仍然是全球重大公共卫生挑战,在埃塞俄比亚等撒哈拉以南非洲国家尤其如此。以社区为基础的抗逆转录病毒药物续药小组作为以患者为中心的方法正在出现,但证据有限。因此,本研究旨在评估在埃塞俄比亚东部接受抗逆转录病毒疗法(ART)的患者中,社区抗逆转录病毒续药小组中的失访率和预测因素。

方法

这是一项基于机构的回顾性队列研究。采用系统随机抽样技术。通过 Kobo 收集工具收集数据,并将其导出到 Stata 中。假设统计学上显著的影响具有 95%置信区间和 P 值 < 0.05。

结果

社区为基础的 ART 续药小组中的失访率为每 100 人年 6.63(95%置信区间:5.78,7.48)。从开始到随访结束,CAG 的中位数持续时间为 9 个月(IQR = 24)。因此,从卫生机构招募的水平、既往失访史和疾病晚期是具有统计学意义的变量。

结论

本研究结果强调了改善社区抗逆转录病毒小组在护理中的使用的重要性。医疗保健计划最终可以改善艾滋病毒感染者的健康结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca74/11339742/bb809e46fc4f/10.1177_23259582241273338-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca74/11339742/bb809e46fc4f/10.1177_23259582241273338-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca74/11339742/bb809e46fc4f/10.1177_23259582241273338-fig1.jpg

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