Vaughn C C, Copeland J G, Cheng K, Austin J, Levinson M
J Heart Transplant. 1985 Sep-Oct;4(5):502-5.
Acute heart rejection; unresponsive to immunosuppressive therapy, results in cardiogenic shock and death. In the absence of another donor heart, a total artificial heart can be used as a suitable bridging device to re-transplantation. A thirty-three year-old man rejected his allograft forty-eight hours after transplantation. A total artificial heart was used for eleven hours until another donor heart became available and was transplanted. During the bridging period, the hemodynamic performance of the mechanical prosthesis was satisfactory. The patient died forty-eight hours after re-transplantation of donor right heart failure due to pulmonary edema. This edema was felt to be related to the long periods of cardiopulmonary bypass. This unique experience illustrates the need for a prompt decision to proceed with cardiac replacement, avoiding long periods of cardiopulmonary bypass, the need for a suitable mechanical device availability, technical expertise in device implantation and allograft transplantation.
急性心脏排斥反应；对免疫抑制治疗无反应，导致心源性休克和死亡。在没有其他供体心脏的情况下，全人工心脏可作为合适的过渡装置用于再次移植。一名33岁男性在移植后48小时发生同种异体移植排斥反应。使用全人工心脏11小时，直到有另一个供体心脏可用并进行移植。在过渡期间，机械假体的血流动力学性能令人满意。患者在再次移植后48小时因供体右心衰竭伴肺水肿死亡。这种水肿被认为与长时间的体外循环有关。这一独特经历表明，需要迅速决定进行心脏置换，避免长时间的体外循环，需要有合适的机械设备可用，以及在设备植入和同种异体移植方面的技术专长。
