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消除初级保健中慢性阻塞性肺疾病管理的障碍:应用2023年更新的加拿大胸科学会药物治疗指南

Breaking down barriers to COPD management in primary care: applying the updated 2023 Canadian Thoracic Society guideline for pharmacotherapy.

作者信息

Kaplan Alan, Babineau Amanda, Hauptman Robert, Levitz Suzanne, Lin Peter, Yang Molly

机构信息

Family Physician Airways Group of Canada, University of Toronto, Toronto, ON, Canada.

Respiratory Health Clinic, Vitalité Health Network, Moncton, NB, Canada.

出版信息

Front Med (Lausanne). 2024 Aug 6;11:1416163. doi: 10.3389/fmed.2024.1416163. eCollection 2024.

Abstract

Chronic obstructive pulmonary disease (COPD) is a highly prevalent yet under-recognized and sub-optimally managed disease that is associated with substantial morbidity and mortality. Primary care providers (PCPs) are at the frontlines of COPD management, and they play a critical role across the full spectrum of the COPD patient journey from initial recognition and diagnosis to treatment optimization and referral to specialty care. The Canadian Thoracic Society (CTS) recently updated their guideline on pharmacotherapy in patients with stable COPD, and there are several key changes that have a direct impact on COPD management in the primary care setting. Notably, it is the first guideline to formally make recommendations on mortality reduction in COPD, which elevates this disease to the same league as other chronic diseases that are commonly managed in primary care and where optimized pharmacotherapy can reduce all-cause mortality. It also recommends earlier and more aggressive initial maintenance inhaler therapy across all severities of COPD, and preferentially favors the use of single inhaler therapies over multiple inhaler regimens. This review summarizes some of the key guideline changes and offers practical tips on how to implement the new recommendations in primary care. It also addresses other barriers to optimal COPD management in the primary care setting that are not addressed by the guideline update and suggests strategies on how they could be overcome.

摘要

慢性阻塞性肺疾病(COPD)是一种高度流行但未得到充分认识且管理欠佳的疾病,与较高的发病率和死亡率相关。初级保健提供者(PCP)处于COPD管理的前沿,在COPD患者从最初识别和诊断到治疗优化以及转诊至专科护理的整个过程中发挥着关键作用。加拿大胸科学会(CTS)最近更新了其关于稳定期COPD患者药物治疗的指南,有几项关键变化对初级保健环境中的COPD管理产生直接影响。值得注意的是,这是首个正式就降低COPD死亡率提出建议的指南,这使该疾病与其他在初级保健中常见管理且优化药物治疗可降低全因死亡率的慢性疾病处于同一水平。它还建议在所有严重程度的COPD中更早且更积极地进行初始维持吸入器治疗,并且优先选择单一吸入器疗法而非多种吸入器方案。本综述总结了一些关键的指南变化,并提供了关于如何在初级保健中实施新建议的实用提示。它还探讨了初级保健环境中COPD最佳管理的其他未被指南更新所涵盖的障碍,并提出了克服这些障碍的策略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/55e4/11333456/20406af8b54d/fmed-11-1416163-g001.jpg

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